Tuesday, 31 March 2026

Mysterious Ancient Culture Forged a Weapon From a Fallen Star

30 March 2026, By, M. Starr

(Mark Garlick/Science Photo Library/Getty Images)

A strange chunk of metal that lay hidden in the soil for thousands of years may shed new light on one of the most mysterious cultures in ancient China.

The approximately 3,000-year-old Sanxingdui artifact appears to be an axe-like object made of iron – which likely came to Earth from space in the form of a meteorite.

It's an extraordinary discovery that sheds light both on the Sanxingdui culture and the use of iron for crafting precious objects long before iron smelting became widespread.

"As the earliest Bronze Age meteoritic iron artefact found in Southwest China," writes a team led by archaeologist Haichao Li of Sichuan University in China, "it fills a critical gap in the region's metallurgical records and provides new insights into early iron use both regionally and globally."


Three fragments that crumbled off the dilapidated artifact. 
(Li et al., Archaeol. Res. Asia, 2026)



Sanxingdui is a major archaeological site in Southwest China, dating back to 2800 to 600 BCE. It reached its peak during the Shang Dynasty between around 1600 and 1050 BCE, and left in its wake iconic, eerie art and evidence of a strong emphasis on ritual.

One type of deposit made by the Sanxingdui people is what archaeologists refer to as "sacrificial pits" in the ritual precinct of the walled city. These are eight pits from which archaeologists excavated some 17,000 extraordinary ritual objects, including bronze masks, figurines, ivory, and jade tools.

The precise purpose of these pits is unknown, but the presence of ash, charcoal, and evidence of burning on some objects suggests the sites may have been used for ritual offerings.

Whatever their purpose, they have provided an invaluable source of artifacts that help us understand the aesthetic and material principles prized by the people of Sanxingdui.

One sacrificial pit, however, yielded a treasure of a kind unlike anything else in the assemblage.

"Among the many artifacts recovered in Sanxingdui, an unusual iron artifact (K7QW-TIE-1) was unearthed from Pit No. 7," the researchers write.

"This artifact was found vertically embedded at the bottom of the eastern wall's southern section. It is elongated in the form of an axe-like tool or weapon."

The object measures about 20 centimeters (8 inches) in length and 5 to 8 centimeters (2 to 3 inches) in width. It was in poor condition, so the researchers carefully extracted the part of the pit wall in which it was embedded and took the whole block back to the laboratory for testing.


A metallographic micrograph of a sample of the artifact. 
(Li et al., Archaeol. Res. Asia, 2026)



The chronology of the surrounding artifacts dates the object to the Shang Dynasty, before iron smelting spread across China. However, X-ray fluorescence revealed that the object is at least 90 percent iron by weight, with 7.41 percent nickel, and the rest trace elements.

That composition, the researchers say, would have been difficult to achieve with the metal-processing techniques of the Late Shang period,

Bronze was the metal of choice for tools, weapons, and jewellery during the Bronze Age – hence the era's name – which in China began around 2000 BCE. The alloy was durable and easily available, made by smelting copper and mixing it with tin and other metals.

Cast iron smelting only took off in China around 800 BCE, when the technology to smelt iron from its ore became widespread, after people discovered how to reach the very high temperatures required for the process.

So the use of iron is unusual for the Bronze Age – but not without precedent. In other places around the world, including other parts of China, some rare and precious artifacts appear to have been made from iron not dug from beneath our feet, but that fell blazing from the sky.

However, the Sanxingdui find suggests this rare material may have been used differently here. Unlike objects from China's Central Plains, which often combined meteoritic iron with bronze, the Sanxingdui artifact appears to have been made entirely from iron.

"The presence of meteoritic iron at Sanxingdui further highlights the distinctive metallurgical practice in Southwest China, in contrast to contemporaneous practices in the Central Plains," the researchers write.

Combined with its discovery in a ritual pit, the find raises the intriguing possibility that the meteoritic iron wasn't just a run-of-the-mill material to the Sanxingdui people, but was precious enough to be included in whatever activity involved accumulating treasure in a pit and setting it ablaze.

"The artifact's fragile state poses significant conservation challenges for further cleaning," the researchers write.

"Future work needs to be undertaken focusing on high-resolution characterization to refine the artifact classification and clarify the relevant functional and ritual roles."



The birth of modern Man
https://chuckincardinal.blogspot.com/

Scientists Track Bees in 3D and Discover Remarkable Secret Navigation Skills

By U. of Freiburg, March 29, 2026

Researchers tracked honey bees in a natural agricultural landscape using a high-speed drone-based system, revealing remarkably precise and individualized flight paths between hive and food source. The findings suggest that bees rely heavily on visual landmarks to navigate, maintaining consistent routes with minimal deviation even across repeated trips. 
Credit: Shutterstock

Honeybees fly consistent, landmark-guided routes with remarkable precision, revealing better navigation than their waggle dance suggests.

A research team at the University of Freiburg, led by neurobiologist and behavioral biologist Prof. Dr. Andrew Straw, investigated how honey bees fly between their hive and a nearby food source. Using a drone, the scientists tracked bees traveling through an agricultural landscape over a distance of about 120 meters (394 feet).

To follow each bee’s route, the team used the “Fast Lock-On (FLO) Tracking” method developed in Straw’s lab. This technique involves placing a tiny reflective marker on the insect. A computer mounted on the drone then analyzes reflected light to detect the bee within milliseconds and continuously monitor its position.

Colored flight paths show the individual routes taken by honeybees in an agricultural landscape: The insects orient themselves using landmarks such as groups of trees and fly to familiar destinations with great precision. 
Credit: Andrew Straw

The findings reveal that every honeybee follows its own distinct path and repeats it with remarkable precision on both outbound and return trips. The bees rely on visual features in the environment to guide their navigation.

“Our tracking system makes it possible for the first time to record high-resolution 3D flight paths of honey bees in natural landscapes,” explains Straw. “Our recordings show that each bee has its own preferred route and flies it very precisely. You could almost say that each bee has its own personality.”


A team from the University of Freiburg shows that honeybees fly individually chosen routes with high precision. 
Credit: Andrew Straw
Precision Navigation and the Role of Landmarks



The researchers analyzed 255 flight paths near the Kaiserstuhl region in Germany. This agricultural area includes hedges, a cornfield, and a tree that blocks the direct line between the hive and the food source. “We found a high degree of precision in the flight paths. Individual bees repeated their individual flight paths nearly exactly on several flights. They often fly just a few centimeters away from their previous paths,” Straw emphasizes.



Prof. Dr. Andrew Straw. Credit: University of Freiburg



The smallest deviations occurred near prominent features such as the tree. In contrast, the greatest variation appeared over the cornfield, where the scenery is visually uniform.

“Our results suggest that visual landmarks aid the bees’ navigation and increase the precision of their flight paths,” explains Straw. In contrast, the bees’ uncertainty increases in visually monotonous environments.

The study also sheds new light on the waggle dance, the behavior bees use to communicate the location of food sources. “It was previously known that the directional information in the waggle dance is not entirely accurate,” explains Straw. For food sources approximately 100 metres away, the directional information in the waggle dance can deviate by around 30 degrees.


Honeybees equipped with small reflector markers enable precise tracking of their flight paths—the results show that individual bees navigate to known destinations much more accurately than the directional information provided by the waggle dance would suggest.
 Credit: Andrew Straw



Rethinking the Accuracy of the Waggle Dance

“Our research has shown that individual bees navigate much more accurately to destinations they are familiar with. Even where their flight paths vary most, they deviate from their individual route by only a few degrees,” says Straw.

“Our results allow us to conclude that the inaccuracy of the waggle dance is not due to the bees’ limited navigational abilities. Rather, individual animals are spatially much more accurately oriented than their dance communication would suggest,” he concludes.


The Life of Earth
https://chuckincardinal.blogspot.com/

This Spice Combo Could Slash Inflammation Hundreds of Times More Effectively

By Tokyo U. of Science, March 31, 2026

Chronic inflammation quietly contributes to serious diseases, but new research suggests that specific combinations of plant compounds, such as those found in mint, eucalyptus, and chili peppers, may work together to suppress it far more effectively than single ingredients.
 Credit: Shutterstock

Researchers have found that common food ingredients can interact inside immune cells in ways that significantly enhance each other’s anti-inflammatory effects.

Chronic inflammation often develops quietly, without obvious symptoms in its early stages. Over time, however, this persistent immune activity can contribute to serious health conditions, including type 2 diabetes, cardiovascular disease, obesity, arthritis, and certain cancers. At its core, inflammation is driven by immune cells that release signaling molecules to respond to injury or infection.

Diet plays an important role in shaping this process. Common foods and seasonings such as herbs, spices, and aromatic plants contain natural compounds known as phytochemicals that can influence inflammatory pathways. These ingredients have been combined in traditional diets and remedies for centuries, long before their biological effects were understood.

Despite this long history, scientists have struggled to explain exactly how plant-based ingredients reduce inflammation. Individual compounds often show anti-inflammatory activity in laboratory experiments, but typically only at concentrations far higher than what people consume through everyday diets.

This gap has led to uncertainty about whether “anti-inflammatory foods” can meaningfully affect the body. Another unresolved question is how different compounds might interact inside cells. It has been hypothesized that combinations of ingredients could produce stronger effects together than individually, but these interactions have rarely been tested or explained at the molecular level.

Testing plant compound synergy in immune cells

To investigate this, a research team led by Professor Gen-ichiro Arimura from the Department of Biological Science and Technology, Tokyo University of Science, Japan, examined how combinations of plant-derived compounds influence inflammation in immune cells. Their study, published in the journal Nutrients, focused on compounds commonly found in mint, eucalyptus, and chili peppers, testing whether pairing them could suppress inflammatory responses more effectively than using each one alone.

This plot shows the measured TNF-α protein concentration released by macrophages as an indicator of inflammation. 
Combining capsaicin (CA) with either menthol (ME) or 1,8-cineole (CI) drastically reduced inflammation levels induced by bacterial lipopolysaccharide protein.
 Credit: Gen-ichiro Arimura/Tokyo University of Science

The team studied macrophages, immune cells that play a central role in inflammation by producing signaling proteins called cytokines. To simulate an inflammatory response, murine macrophages were exposed to lipopolysaccharide, a bacterial component frequently used in laboratory models. The researchers then treated the cells with menthol (from mint), 1,8-cineole (from eucalyptus), capsaicin (from chili peppers), and β-eudesmol (from hops and gingers), both individually and in specific combinations.

They evaluated the effects using gene expression analysis, protein measurements, and calcium imaging. The team also investigated whether these compounds acted through transient receptor potential (TRP) channels, which are proteins in the cell membrane that respond to chemical and physical signals and regulate calcium activity, a key factor in immune cell behavior.

Synergistic effects amplify anti-inflammatory response

On its own, capsaicin showed the strongest anti-inflammatory effect among the compounds tested. However, the most notable results emerged when compounds were combined. “When capsaicin and menthol or 1,8-cineole were used together, their anti-inflammatory effect increased several hundred-fold compared to when each compound was used alone,” highlights Prof. Arimura.

Further analysis helped clarify why this happens. Menthol and 1,8-cineole influenced inflammation through TRP channels and calcium signaling, while capsaicin appeared to act through a separate pathway that does not depend on TRP. “We demonstrated that this synergistic effect is not a coincidence, but is based on a novel mode of action resulting from the simultaneous activation of different intracellular signaling pathways,” says Prof. Arimura. “This provides clear molecular-level evidence for the empirically known effects of combining food ingredients.”

Implications for diet and functional foods

These findings offer insight into how combinations of plant compounds may produce measurable biological effects even at the relatively low levels typically found in food. They also point to new possibilities for developing functional foods, supplements, seasonings, or fragrances designed to deliver stronger effects using smaller amounts of active ingredients.

More broadly, the results support the idea that the benefits of plant-rich diets may arise from interactions among many compounds working together, rather than from any single “super” ingredient. Although further research in animal models and humans is needed, this study provides a clearer framework for understanding how everyday foods and natural compounds may help regulate chronic inflammation and support long-term health.



The Life of Earth
https://chuckincardinal.blogspot.com/

Monday, 30 March 2026

Scientists Identify Biological Pathway That Could Reverse Memory Loss

By Arc Institute, March 29, 2026

Age-related memory decline may not originate solely in the brain, but instead reflect changes elsewhere in the body. New research suggests signals from the gut can interfere with brain circuits involved in memory. 
Credit: Shutterstock

Gut microbiome changes may drive age-related memory loss via inflammation and disrupted brain signaling, but interventions in mice show this process can be reversed.

Memory tends to decline with age, but this pattern is not the same for everyone. Some individuals remain mentally sharp even at 100, while others begin experiencing noticeable memory issues much earlier in life.

Although it is often assumed that cognitive decline is caused by aging and deterioration within the brain itself, growing evidence suggests that other parts of the body also play a role. Signals from organs throughout the body can influence how the brain processes and stores information. Research has also shown that the gut microbiome can affect learning, behavior, and memory. However, the exact mechanisms behind these connections remain unclear, including which molecules, microbes, and signaling pathways are involved, and whether they could be targeted to prevent or reverse memory loss.

A recent study published in Nature found that changes in the aging gastrointestinal system produce molecules that interfere with a key gut-brain signaling pathway, contributing to cognitive decline in mice.

Interoception and the Gut-Brain Connection

The body’s five senses, known as exteroception, include sight, hearing, taste, smell, and touch, and tend to weaken with age. Less understood is interoception, which refers to how the brain monitors internal bodily states to maintain balance and function. The vagus nerve plays a central role in this process, carrying information from organs such as the heart, intestines, lungs, and liver to the brain.

The researchers found that signals traveling from the intestine to the brain through the vagus nerve help protect against cognitive decline in mice. Activating specific sensory neurons in the gut that connect to this nerve restored more youthful cognitive performance in older mice. These findings, thus, suggest that internal sensory systems, like external senses, may deteriorate with age. This raises important questions about what drives this decline and how it might be reversed.

The composition of the gut microbiome changes over time, including shifts in microbial species and their metabolic activity. To test whether these changes influence memory, the researchers transferred microbiomes from older mice into younger ones and evaluated their cognitive performance.

Young mice receiving older microbiomes showed impaired memory, similar to older animals. However, removing the microbiome with antibiotics restored cognitive function. Interestingly, mice raised without any microbiome showed slower cognitive decline as they aged compared to normal mice. These findings indicate that factors produced by aging gut microbes may contribute to memory loss.

Microbiome Changes and Cognitive Decline

The researchers identified a likely contributor: a bacterium called Parabacteroides goldsteinii. This microbe produces medium-chain fatty acids (MCFAs), which increase with age. Elevated MCFA levels activate immune cells in the gut, triggering the release of inflammatory molecules. One such molecule, IL-1β, was found to disrupt the function of vagal sensory neurons. The study traced this chain of events from microbial activity in the gut, through immune signaling, into the vagus nerve, and ultimately to the hippocampus, a brain region essential for memory.


In this figure, an intestinal immune cell detects medium-chain fatty acids produced by aging gut bacteria through the GPR84 receptor, releasing inflammatory molecules that block signaling along the vagus nerve to the hippocampus. Disruption of this gut-brain pathway drives age-associated cognitive decline. Credit: Thaiss Lab




Several interventions were able to restore cognitive function in mice already experiencing decline. While antibiotic treatment improved memory, it is not a practical long-term solution. A more targeted method involved using a bacteriophage, a virus that specifically affects P. goldsteinii. This approach reduced MCFA levels and improved memory performance.

Another promising strategy focused on directly stimulating the vagus nerve. Treatments using the gut hormone CCK or GLP-1 receptor agonists, similar to drugs like Ozempic, successfully reversed memory deficits in older mice.

Reframing Brain Aging Through the Body

These findings challenge the traditional view that cognitive decline is driven solely by changes in the brain. Instead, they suggest that processes in other parts of the body can influence and potentially reverse age-related memory loss using treatments that are already available or under development.

Because the research was conducted in mice, it is not yet clear whether the same mechanisms apply to humans. Further studies are underway to explore this possibility and determine how these findings might translate to clinical use.

There is some early evidence supporting the idea in humans. Vagus nerve stimulation is already used to treat conditions such as severe epilepsy and recovery after stroke. Patients receiving this treatment have reported improvements in cognitive function, suggesting that enhancing vagus nerve activity may also help counter memory loss.

Future Research and Clinical Implications

Other factors, including chronic inflammation or infection, may also impair vagus nerve function through similar pathways. Future research will be needed to determine whether stimulating this nerve can improve cognitive outcomes in these cases, as well as in more severe conditions such as neurodegeneration and dementia.


The Life of Earth
https://chuckincardinal.blogspot.com/

3,500-Year-Old Loom Discovery Reveals Secrets of Bronze Age Weaving

By Antiquity, March 29, 2026

Reconstruction of a Bronze Age loom, which the example from Cabezo Redondo may have looked like. 
Credit: Antiquity

A reconstructed Bronze Age loom from Cabezo Redondo reveals advanced textile production, including potential early twill weaving, suggesting a shift toward more complex fabrics and wool use.

Researchers have analyzed and partially rebuilt a warp-weighted loom from the second millennium BC site of Cabezo Redondo in Spain, offering a rare look at how textile technology developed in the western Mediterranean during the Bronze Age.

Warp-weighted looms were widely used across prehistoric Europe and the Mediterranean to make fabrics. In this type of loom, threads hang vertically and are kept tight by clay or stone weights attached at the bottom.

Because these looms were made from wood and plant-based materials, they seldom survive in the archaeological record. As a result, most knowledge of early textile production has come from studying loom weights rather than the looms themselves.

Limits of Archaeological Evidence

“The existence of textile production in Bronze Age southeastern Iberia was well established, particularly through the study of loom weights and spindle whorls,” states lead author of the research, Dr. Ricardo E. Basso Rial from the University of Granada. “However, the wooden components of looms themselves are rarely preserved, which has severely limited our ability to reconstruct loom morphology, spatial organization, and weaving practices in detail.”

At Cabezo Redondo, researchers uncovered charred wooden beams and plant fiber ropes alongside clay loom weights at a Bronze Age settlement in southern Spain. These remains have been identified as parts of a warp-weighted loom.

This find is one of the best-preserved examples of its kind in the western Mediterranean and offers an unusual chance to better understand how textiles were made in Bronze Age Iberia.

Reconstructing the Ancient Loom

By studying the preserved wood and weights, the team was able to partially reconstruct how the loom was built and used.

The wooden elements were made from Aleppo pine, a tree native to the area. The loom weights stand out because they are much lighter than others found across Mediterranean Iberia, which may indicate they were designed for producing finer or more varied fabrics.

“The characteristics of the loom weights suggest that this loom was capable not only of producing open tabby fabrics but also potentially denser and more technically complex textiles, probably including early twill weaves,” says Dr. Basso Rial. “This represents a notable advance in our understanding of Bronze Age textile technology in Iberia.”

Advances in Textile Technology

Tabby weaving, often done with plant fibers like flax, was the dominant technique from the Neolithic through the Bronze Age. Twill weaving, on the other hand, did not become common until the early 1st millennium BC.

Twill fabrics were usually made from wool, which suggests that Cabezo Redondo may have played a role in a broader “textile revolution” marked by increased use of wool and more diverse fabric production.

“This discovery allows us to see not just the partial tools that are usually preserved, but the loom itself—frozen at the moment it was in use nearly 3,500 years ago—offering a rare glimpse into the everyday craft of Bronze Age weaving,” concludes Dr. Basso Rial.



The birth of modern Man
https://chuckincardinal.blogspot.com/

Ancient Whale Hunters of Brazil Challenge Long-Held Scientific Assumptions

By U. Autonoma de Barcelona, March 29, 2026

Indigenous communities hunting cetaceans 5,000 years ago. 
Credit: Patricia del Amo Martín. ICTA-UAB

Ancient Brazilian communities hunted whales earlier than previously thought, using advanced technologies. The discovery reshapes views of early maritime societies and provides new ecological insights.

Whaling dates back much deeper in history than previously recognized. A new study by the Institute of Environmental Science and Technology at the Universitat Autònoma de Barcelona (ICTA-UAB) and the university’s Department of Prehistory shows that Indigenous groups in southern Brazil were hunting large whales 5,000 years ago, about 1,000 years before similar practices are documented in Arctic and North Pacific cultures.

Published in Nature Communications, the research focuses on communities around Babitonga Bay (Santa Catarina) that built sambaquis, large shell mounds created by coastal societies during the Holocene.

These groups developed specialized methods for hunting whales much earlier than earlier archaeological interpretations suggested. The findings challenge long-held assumptions that large-scale whaling began in Northern Hemisphere societies between 3,500 and 2,500 years ago.

Harpoons foreshaft found in a human burial in Morro do Ouro. 
Credit: ERC-TRADITION

The study, led by ICTA-UAB researchers Krista McGrath and André Colonese with an international team, examined hundreds of whale bones and bone tools recovered from sambaqui sites in Babitonga Bay. These materials are now preserved at the Museu Arqueológico de Sambaqui de Joinville in Brazil. Since many original sites have disappeared, the collection offers a rare and valuable record that would otherwise be lost.

Advanced Tools and Scientific Analysis of Cetacean Remains

Researchers used a combination of zooarcheology, typological study, and advanced molecular techniques (ZooMS) to analyze the remains. They identified species including southern right whales, humpback whales, blue whales, sei whales, sperm whales, and dolphins. Many of the bones show cut marks linked to butchering.

The team also documented large whalebone harpoons, among the biggest found in South America. Together, this evidence, including whale remains found in burial contexts and the presence of coastal species, strongly supports active hunting rather than reliance on stranded animals.


Krista McGrath (first author) analyzing one of the harpoons.
 Credit: ERC-TRADITION




“The data reveals that these communities had the knowledge, tools, and specialized strategies to hunt large whales thousands of years earlier than we had previously assumed,” says Krista McGrath, lead author of the study.




Harpoons foreshaft found in a human burial in Morro do Ouro. 
Credit: ERC- TRADITION



The findings also offer insight into past ecosystems. The large number of humpback whale remains suggests that these whales once ranged much farther south than their current main breeding grounds off Brazil. “The recent increase in sightings in Southern Brazil may therefore reflect a historical recolonization process, with implications for conservation. Reconstructing whale distributions before the impact of industrial whaling is essential to understanding their recovery dynamics,” says Marta Cremer, co-author of the paper.
Rethinking Sambaqui Societies and Maritime Culture

In addition to redefining the timeline of whale hunting, the study provides a more in-depth look at the economies, technologies, and daily life of postglacial societies along South America’s Atlantic coast. According to André Colonese, senior author of the study, “This research opens a new perspective on the social organization of the Sambaqui peoples. It represents a paradigm shift – we can now view these groups not only as shellfish collectors and fishers, but also as whalers.”

Dione Bandeira, a Brazilian archaeologist with more than 20 years of experience studying sambaquis, adds that “the results reveal a practice that made a significant contribution to the long-term and dense presence of these societies along the Brazilian coast.”

Remains of the shell mound Morro do Ouro (in Joinville, Santa Catarina state – dated to 4500 cal BP). Credit: ERC-TRADITION

The Sambaqui peoples incorporated marine resources into their cultural systems and built a complex maritime way of life. Their society relied on specialized tools, coordinated group efforts, and rituals connected to hunting large marine animals. This Indigenous history, not recorded in written form, has been preserved through museum collections and ongoing efforts to protect remaining sambaqui sites from the effects of urban growth in Brazil.

Ana Paula, director of the Museu Arqueológico de Sambaqui de Joinville, notes that “the collections safeguarded at the Sambaqui Archaeological Museum in Joinville, especially the Guilherme Tibúrtius Collection, highlight the richness and vast potential of information on ancestral peoples that can still be explored in depth.”


The birth of modern Man
https://chuckincardinal.blogspot.com/

Sunday, 29 March 2026

Chuck's picture corner to March 29, 2026

The week has warmed up here in Cardinal and the snow has mostly melted away. But for the first time since I've lived here the basement has flooded inches a day. I'm still having to pump water off of the lowest floor twice a day to keep the furnace dry and working . It's on a higher section of floor by about 8".

Outside a south facing window this morning.

The ginkgo is coming along.

the summer garden begins (plum tomatoes)

This year's collection of tomatoes, plum, celebrity, bonny best 

Peppers are popping, these are the first seeded, they are hot pepper varieties.

the peppers get topped with plastic for extra humidity till they sprout.

last nights sunset. The landscape turned white overnight with about an inch of snow.

earlier in the week out the office window, facing west.

out great grand ma's bedroom window facing east before 7 am 

starlings enjoy some lawn bugs

morning at Rachelle's

A little more work done on Rachelle's fireplace. Now ready for grouting. The grout will be black. Then it's on to brick tiles up to at least the mantel.


Cheers
enjoy the day.
https://chuckincardinal.blogspot.com/


Couples Share a Surprising Percentage of Gut Bacteria That May Impact Health

29 March 2026, ByC. Meehan and J. Mwerinde, The Conversation

(Eric Cahan/The Image Bank/Getty Images)

When living with a partner, you might be sharing more than just the same home, lifestyle and interests. You might also share various microscopic organisms residing on and in you.

This community of microorganisms, which consists of mainly bacteria, viruses and fungi, is known collectively as the human microbiome. The various microbiomes found throughout the body all play an important role in health.

From birth, the human microbiome is shaped by our interactions with our mother, who introduces diverse microorganisms that build our immune and digestive systems. As we get older, social interactions with our close community continue influencing this delicate ecosystem.

The people we live with have huge influence on what microbes we have in our microbiome. In fact, it's thought that partners share around 30% of their resident microbes in the gut alone.

But it isn't just the microbes in your gut that may be similar to your partner. The microbes in many other parts of the body may also be shared with your loved one – and this could potentially affect your health.

Gut microbiome

Diet and lifestyle are thought to have the greatest influence on the gut microbiome's make-up. But studies on couples have found that living with your partner can also influence the microbiome.

Couples living together may share 13% to 30%of their gut bacteria. This was true even when diet (which many couples share) was factored out.
Research also shows that couples who live together have greater microbial diversity compared to people who live alone.

This is good news for couples who co-habitate, as a more diverse gut microbiome is correlated with lower risk of irritable bowel syndrome, cardiovascular diseases and potentially high blood sugar.

But it might not all be good news. Research shows that some of the bacterial species couples share can have varying effects on health.

Take the bacteria from the Ruminococcus family. While some species of Ruminoccocus benefit health, others have been linked to negative health outcomes, including diabetes and irritable bowel syndrome.

So these bacteria may not always offer the same benefits in different demographics. This highlights the complexity of resident gut bacteria and their health impacts.

Oral microbiome

Sharing an oral microbiome with our partners might seem obvious considering we regularly exchange saliva when we kiss. A ten-second kiss alone can exchange up to 80 million bacteria. The more kisses a couple shares, the more shared salivary bacteria they will have.

Although most of these bacteria will quickly pass through our mouth and into our gut when we swallow saliva, research show that couples actually share many of the same longer-term tongue microbes that form the foundation of the oral microbiome. Research even suggests that 38% of the oral microbiome is shared in couples living together – compared to only 3% in couples who don't live together.

Sharing this proportion of your oral microbiome could have many potential health effects.

A healthy oral microbiome is important for protecting against tooth decay and it has anti-inflammatory properties. Some researchers also suggest the oral microbiome's health effects may extend as far as the gut and nervous system.

But some of the bacteria that couples tend to share may also have potentially harmful health effects.

Couples are more likely to have similar numbers of the bacteria Neisseria in their gut compared to single people. Neisseria can reside in the mouth for long periods of without causing disease.

Some Neisseria bacteria can be harmful and may cause meningitis. Yet some Neisseria bacteria actually fight against these meningitis-causing species, stopping them from overgrowing and causing harm.

So while you may want to avoid kissing someone when they're poorly for obvious reasons, it turns out that a kiss even when you're healthy can transfer all sorts of bacteria between the two of you.

More research is needed to really understand what overall effect sharing these bacteria with your partner has on health.

Skin microbiome

The skin microbiome is the most unique and personalised microbiome, tailored to each person. It's even sometimes referred to as our microbial fingerprint.

Being the most exposed microbiome, the skin microbiome has evolved to be adaptable to external factors such as the climate and cosmetic products. No matter what, these bacteria work hard to remain at an equilibrium.

Close contact with our partners – and even pets – has a huge influence on what bacteria live on our skin. After comparing the gut and oral microbiome, researchers found the skin microbiome to be the most similar among couples.


(Halfpoint Images/Moment/Getty Images)



It isn't just the bacteria on your arms or hands that are shared, either. Research shows that couples shared 35% of the bacteria living on their feet, and around 17.5% of the bacteria on their eyelids.

You may not even need to touch your partner to have the same skin bacteria as them. Factors such as sleeping in the same bed and walking on similar surfaces are thought to explain why such a large proportion of our skin microbiome is similar.

This is because humans naturally shed bacteria in a similar way as dogs shed fur. We leave traces of our bacteria on everything we touch – and we also easily pick up bacteria from our environments.

The shared effect of living together on the skin microbiome is so great that researchers were able to use computer models to accurately predict 86% of cohabiting couples based off of their individual bacterial samples alone.

But while it's clear that couples share much of the same skin microbiome, the health effect that this has is not currently known.

While sharing bacteria with your partner may sound alarming, there's often no cause for concern. Bacteria teach our bodies how to fight infections, they help us digest foods and even produce key nutrients. The bacteria we share with our partners are often harmless and sometimes benefit our health rather than hindering it.



The Life of Earth
https://chuckincardinal.blogspot.com/

“Super Bizarre” – Neuroscientists Discover That Adult Brain Is Filled With Millions of “Silent Synapses”

By SciTechDaily.com, March 29, 2026

Using advanced imaging techniques, researchers discovered that many of these dormant connections reside on tiny structures called filopodia, far more abundant in the adult brain than previously believed. Credit: Stock

Scientists have uncovered a surprisingly large reserve of “silent synapses” in the adult brain—unused neural connections that can be rapidly activated to store new memories.

Learning something new without erasing what you already know is one of the brain’s hardest balancing acts. Now, MIT neuroscientists have uncovered a hidden feature that may make this possible: a vast reserve of “silent synapses” in the adult brain that can be switched on to store new memories.

These synapses are real physical connections between neurons, but they remain inactive until they are needed. In adult mice, the researchers found that about 30 percent of synapses in the brain’s cortex fall into this silent category, far more than scientists once expected.

For years, silent synapses were thought to exist only in infancy, when the brain is rapidly wiring itself in response to new experiences. They were believed to largely disappear early in life. The new findings challenge that view and suggest the adult brain keeps a large запас of these unused connections on standby.

“This lets the brain create new memories without overwriting the important memories stored in mature synapses, which are harder to change,” says Dimitra Vardalaki, an MIT graduate student and lead author of the study.

A built-in workaround for memory overload

The human brain is estimated to contain hundreds of trillions of synapses, forming a dense and constantly shifting network. Every new memory depends on adjusting this network. But constantly modifying existing connections risks corrupting older, important information.


Caption:MIT researchers have discovered that the adult mouse brain contains millions of silent synapses, located on tiny structures called filopodia.
 Credit: Dimitra Vardalaki and Mark Harnett



The new research points to a different strategy. Instead of reshaping established circuits, the brain can recruit silent synapses and convert them into active ones. This preserves older memories while still allowing new learning.

This idea aligns with long-standing theories that the brain must strike a balance between stability and flexibility. Some connections need to remain stable to protect long-term knowledge, while others must stay adaptable to encode new experiences.

An accidental discovery

The MIT team did not set out to find silent synapses in adults. They were studying how dendrites, the branching extensions of neurons, process incoming signals. To do this, they used a technique called eMAP (epitope-preserving Magnified Analysis of the Proteome), which physically expands brain tissue so proteins can be mapped with extremely high resolution.

What they saw surprised them.

“The first thing we saw, which was super bizarre and we didn’t expect, was that there were filopodia everywhere,” says senior author Mark Harnett.

Filopodia are tiny, finger-like protrusions extending from dendrites. Because they are so small, they have been difficult to study and their function has remained unclear. Using eMAP, the researchers found them spread widely across the adult mouse brain, including the visual cortex, at levels about 10 times higher than previously reported.

When the team examined these structures more closely, they found a key clue. The synapses on filopodia had NMDA receptors but lacked AMPA receptors.

In normal synapses, both receptor types are needed to pass electrical signals triggered by the neurotransmitter glutamate. Without AMPA receptors, NMDA receptors remain blocked under typical conditions, leaving the synapse functionally silent.

Switching them on

To confirm that these structures were truly silent synapses, the researchers measured their electrical activity using a refined patch clamp technique. They delivered controlled bursts of glutamate to individual filopodia.

Nothing happened, at least at first.

Only when the researchers experimentally removed the block on NMDA receptors did the synapses respond, confirming that they were inactive under normal conditions.

The next question was whether these silent connections could be activated in a realistic way. The answer was yes.

When glutamate release was paired with a brief electrical signal inside the neuron, AMPA receptors quickly accumulated at the synapse. Within minutes, the once silent connection became fully functional.

This process did not work on mature synapses.

“If you start with an already functional synapse, that plasticity protocol doesn’t work,” Harnett says. “The synapses in the adult brain have a much higher threshold, presumably because you want those memories to be pretty resilient.”

Filopodia, by contrast, act like ready-to-use slots for new information.

Why this matters for learning and aging

The discovery suggests the adult brain maintains a large pool of flexible connections that can be recruited on demand. This could help explain how people continue learning throughout life without constantly disrupting older memories.

It also raises new questions about what happens as the brain ages.

“It’s entirely possible that by changing the amount of flexibility you’ve got in a memory system, it could become much harder to change your behaviors and habits or incorporate new information,” Harnett says.

If silent synapses decline with age or disease, that could help explain why learning new skills or adapting to change becomes more difficult over time.

The findings also hint at future possibilities. If scientists can identify the molecular mechanisms that control filopodia and silent synapses, they may be able to develop ways to restore learning capacity in aging brains or in conditions that affect memory.




The Life of Earth
https://chuckincardinal.blogspot.com/

Saturday, 28 March 2026

Scientists Identify “Good” Bacteria That May Prevent Long COVID

By U. of Louvain, March 21, 2026

Long COVID continues to affect millions of people worldwide, and scientists are still trying to understand why some patients recover while others experience lingering symptoms. A new study points to an intriguing player within the respiratory microbiome — a naturally occurring bacterium that may influence how the body responds long after infection has passed.
 Credit: Shutterstock

A small microbe in the respiratory tract may hold important clues about why long COVID persists.

According to the WHO, about 6% of people worldwide who get COVID-19, roughly 400 million people, later develop a long-lasting form of the illness. That shows the condition remains a significant public health challenge.

In 2021, during the COVID-19 pandemic, the University of Louvain (UCLouvain, Belgium) and its hospital, the Cliniques universitaires Saint-Luc, launched a large-scale study to see whether long-term symptoms could be predicted during the acute phase of infection. The goal was to better understand the biological mechanisms involved and potentially identify a preventive treatment.

A Bacterium Linked to Recovery

After five years of research, scientists identified an important role for Dolosigranulum pigrum, a bacterium that naturally lives in the respiratory microbiome. Higher levels of this bacterium were associated with a lower likelihood that long Covid symptoms would persist.

Jean Cyr Yombi, Leïla Belkir, and Julien De Greef, UCLouvain professors and infectious disease specialists at the Cliniques universitaires Saint-Luc, examined the severity of long Covid symptoms in 156 patients. They focused mainly on severe fatigue, cognitive problems, and respiratory issues (shortness of breath).

Laure Elens and Patrice Cani, also UCLouvain professors, along with Bradley Ward, a postdoctoral researcher at the UCLouvain Louvain Drug Research Institute, then analyzed blood samples and nasopharyngeal swabs for molecular signatures linked to this more severe form of the disease. These signatures may help explain why symptoms persist in some patients but not in others.

Clues From the Respiratory Microbiome

UCLouvain and Cliniques universitaires Saint-Luc researchers stated, “This study suggests that certain so-called protective bacteria in the respiratory microbiome may be associated with improved recovery following viral respiratory infections (such as long Covid or influenza), and that their alteration (particularly in the context of severe infection or non-targeted antibiotic therapy) may influence longer-term clinical outcomes.”

In simpler terms, when this bacterium is present in higher amounts, it appears to help protect against long Covid or severe influenza (through a mechanism that has yet to be elucidated). When it is present at low levels, researchers found a greater tendency toward developing a persistent form of the disease.

Implications for Future Treatments

Researchers already knew this bacterium had a protective effect in infectious influenza. The new findings, published in Microbiology Spectrum, add to the evidence that Dolosigranulum pigrum may be beneficial.

Scientists hope the discovery will speed up research and support new treatment strategies, including the possible development of a probiotic, for example, in the form of a nasal spray, that could be used before winter to help protect people from severe infectious diseases such as Covid-19 or influenza.

The study also found that non-targeted antibiotics can affect the respiratory microbiome’s ability to defend against severe infections. That is another reason careful antibiotic use remains important.



The Life of Earth
https://chuckincardinal.blogspot.com/