Tuesday, 19 May 2026

Scientists Keep Finding Major Discoveries Lurking in Museum Backrooms

18 May 2026, By M. Starr

(Hill Street Studios/DigitalVision/Getty Images)

Museums are among the most expansive resources humans have created.

For most of us, these edifices display rich collections of treasures and knowledge that transport us through time.

For scientists, they're a treasure of a different kind.

In vast warehouses inaccessible to the public, many museums store hoards of more artifacts that rarely see the light of day, and were accumulated faster than humans can study them.

That's why so many discoveries are made not in the field, but in museum backrooms, among wonders half-forgotten for decades.

To celebrate International Museum Day, here are some of our favorite recent discoveries that only emerged when the right person came along to make them.

The oldest known whale bone tools

In a bid to make sense of the hundreds of prehistoric artifacts squirreled away in museums across Europe, a team of archaeologists sat down and compiled a comprehensive catalog using a suite of techniques to date the artifacts and find out what they were made of.

Their results yielded around 150 tools made from whale bone, arising from the Magdalenian culture that occupied coastal and inland regions of western Europe some 19,000 to 14,000 years ago – the earliest known of their kind.


This whale bone point was found in the Duruthy rock shelter in France. 
(Alexandre Lefebvre)



This discovery reveals interesting new details about the whales that once inhabited the Bay of Biscay and how humans interacted with their remains.

"Even old collections, excavated more than one century ago with field methods now outdated, and stored in museums for a long time, can bring new scientific information when approached with the right analytical tools," University of Toulouse-Jean Jaurès archaeologist Jean-Marc Pétillon told ScienceAlert.

Metal from the sky

The Treasure of Villena – discovered more than 60 years ago in 1963 in what is now Alicante in Spain – wasn't exactly moldering away in a storeroom.

As one of the most important examples of ancient goldsmithing in Europe, forged more than 3,000 years ago during the Iberian Bronze Age, it was revered but still somewhat overlooked.


The iron-and-gold hemisphere, which has a maximum diameter of 4.5 centimeters (1.77 inches). 
(Villena Museum)



Then, in 2024, it yielded a surprise. Scientists analyzed two oddities in the collection, a bracelet and a hemisphere made from dull brown material – and found they were made, not from earthly metal, but with iron from meteorites that fell from the sky – in a time before the advent of iron smelting technology.

"The available data suggest that the cap and bracelet from the Villena Treasure are currently the first two pieces attributable to meteoritic iron in the Iberian Peninsula," the researchers wrote.

https://www.youtube.com/watch?v=M4kUXxcS9Io&t=3s

Not a mammoth

It made sense that large bones found inland in the heart of Alaska were identified as belonging to a woolly mammoth and not examined for 70 years.

However, when researchers finally studied the bones as part of a program launched in 2022, radiocarbon dating revealed that the animal that left them lived long after mammoths had gone extinct.


Images of some of the bones. 
(University of Alaska Museum of the North)



Comparison of the bones' mitochondrial DNA with modern species revealed an even bigger surprise: It was not one animal, but two, and they were both whales.

"How did the remains of two whales that are more than 1,000 years old come to be found in interior Alaska, more than 400 km (250 miles) from the nearest coastline?" the researchers queried.

It's a question that remains to be answered.

Darwin meets lasers

Sometimes it's not the specimen, but the method of studying it that reveals new information.


Some of the specimens collected by Charles Darwin in the 19th century. (Dr Sara Mosca, STFC Central Laser Facility)



Some 200 years ago, legendary naturalist Charles Darwin collected hundreds of specimens, preserved in sealed jars. The problem is that many different fluids were used for specimen preservation, and it was unknown which of them Darwin had used.

We can't just unseal the jars and take a peek – that could destroy the delicate remains – so, in a paper published in January 2026, scientists detailed the way they used laser light to identify the methods Darwin had used.

Interestingly, he had different fluids for different kinds of animals – and this information, the scientists said, will help them continue to care for these precious specimens for future generations.

A dinosaur herd written in opal

Australia is one of the only places in the world with the right conditions for fossil opalization – the replacement of bone with shimmering rainbow opal.


An opalized Fostoria dhimbangunmal bone. 
(Robert A Smith/Australian Opal Center)



Many of these specimens are stunningly beautiful, but with opal being so valuable, they often have a checkered history. Some are squirreled away in private collections; others get traded; and some go unstudied for years.

A collection of opalized fossils first discovered in 1984 was finally examined by paleontologists decades later, after it was recovered and donated in 2015.

As described in a 2019 paper, the jumble of bones turned out to be the remains of at least four separate animals, all belonging to a previously unknown dinosaur species.

The species was named Fostoria dhimbangunmal. It roamed the eastern flank of Australia during the mid-Cretaceous, in herds large enough that this group stayed together even after death, turning into beautiful gemstones together.

Three-eyed brains

The Burgess Shale truly is a fossil cornucopia like no other. This spectacular, 508-million-year-old fossil bed is so rich that, often, paleontologists can only collect them and put them aside to create an archive that is slowly being worked through.


A reconstruction of Stanleycaris hirpex hovering above its fossil. 
(Sabrina Cappelli © Royal Ontario Museum)



One species, Stanleycaris hirpex, is a strange three-eyed animal known as a radiodont, related to modern arthropods.

Hundreds of Stanleycaris fossils have been collected, but it wasn't until a 2022 paper – two decades after they were discovered – that scientists revealed just how exciting these tiny animals really are.

In 84 specimens from a collection of 268 Stanleycaris fossils, the brain was preserved in exquisite detail – a discovery that shed new light on the evolution of arthropod brains.

"We can even make out fine details such as visual processing centers serving the large eyes and traces of nerves entering the appendages," said evolutionary biologist Joseph Moysiuk of the University of Toronto.

The world has more marvels than we currently have time to examine.

While museums offer a place of learning for many of us, for scientists, they provide a place to keep irreplaceable treasures safe until the right researcher arrives to unravel the secrets they hold.


The Life of Earth
https://chuckincardinal.blogspot.com/

Fog Is Teeming With Life, And It May Be Doing Us a Surprising Favor

19 May 2026, By M. Irving

(Daniel Garrido/Moment/Getty Images)

There's something living in the fog – but you'll be glad to know that it's mostly friendly.

Researchers at Arizona State University and Susquehanna University have found that bacteria are living and growing inside droplets of water in fog, at concentrations comparable to seawater.

While it does mean fog isn't as sterile as it may seem, those microbes are at least earning their keep: They've been found to break down pollutants in the air.

From ground-level sneezes to the highest of clouds, it's long been known that bacteria are floating around in the atmosphere in decent numbers.

But it's less clear whether these microbes are actively living in these airborne environments, or are just passing through on their way to other habitats.

Fittingly, fog is even more mysterious.

"There's very limited knowledge about what kinds of bacteria are present in fogs, which are like clouds at the ground level," says Thi Thuong Thuong Cao, a microbiologist at Arizona State University (ASU).


The research team's experimental setup for capturing fog samples. 
(Thi Thuong Thuong Cao)



To investigate, the researchers on the new study collected air samples before, during, and after fog events on 32 different occasions over a two-year period.

To control for wind blowing everything around and messing with readings, the team specifically examined radiation fog, a type that forms in calm, still air overnight.

And sure enough, a sizable microbiome was detected in that chilly morning air.

Bacteria were present in less than one percent of fog droplets. That doesn't sound like much, but it averages to around 1 million 16S rRNA gene copies – a common marker for estimating bacterial abundance – per milliliter of water.


Concentration of bacterial 16S rRNA gene copies in air samples collected before and after six fog events in 2022. 
(Cao et al., mBio, 2026)



"When you take all of the droplets together, the concentration of bacteria is the same as in the ocean," says Ferran Garcia-Pichel, a microbiologist at ASU.

To answer the question of which bacteria are present, the team conducted genetic analyses. This revealed that those in the Methylobacterium genus dominated the picture.

And they didn't seem to be inert, either.

"If they are growing, then the droplets are a habitat. That's a mindset change," says Ferran Garcia-Pichel.

In a subsample of six fog events, the team found that even after the fog cleared, the air contained around 45 percent more bacteria than at the same location before the fog settled in.

That suggests that something about the foggy atmosphere is actively culturing the bacteria.

"We observed them under the microscope to see that yes, the bacteria are getting bigger and they're dividing, so there is growth," says Cao.

Methylobacteria are known to eat volatile carbon compounds such as formaldehyde, so the team suspected this might be the source of their growth.

To check, the researchers incubated samples of fog water and measured how levels of these compounds changed over time.

Unsurprisingly, these levels dropped – but what was surprising was the speed with which the compounds were consumed.

A foggy Pennsylvania field has a secret: Its droplets are home to 'pollutant-eating' bacteria. 
(Thi Thuong Thuong Cao)

"Existing formaldehyde at the start of the incubation was swiftly consumed to undetectable levels," the researchers write, "roughly 200-fold faster than rates measured elsewhere in cloud water."

That's much too fast to purely be a source of food, the team says. Instead, it's probably for "detoxification purposes" as well, since high levels of formaldehyde can be toxic to the bacteria.

The good news is that these compounds are pollutants for us too, meaning this aerial microbiome may have a cleansing effect. Exactly how beneficial this is in the real world will require more research, though.

"The sky's the limit," Garcia-Pichel says.


The Life of Earth
https://chuckincardinal.blogspot.com/

Monday, 18 May 2026

The Evolution of Cannabis: 28 Million Years of Secrets Hidden From You

Mysteries of the World, Apr 26, 2026

(Use the link to watch on ytube for english, Chuck)

About 28 million years ago, a small plant emerged on the slopes of the ancient Tibetan Plateau that was destined to change the course of human history.

 Cannabis is one of the most mysterious and controversial plants on Earth, and its evolutionary history is far more astonishing than you might imagine.

 In this video, we'll explore the complete evolution of cannabis: from its origins in the high steppes of Asia to its emergence as a companion plant 12,000 years ago—long before wheat, corn, and potatoes. You'll learn how plate tectonics literally created the conditions for this plant's emergence, why cannabis and hops (the basis of beer brewing) turned out to be genetically related, and how a groundbreaking 2021 study involving whole-genome sequencing has revolutionized scientists' understanding of marijuana's origins. 

But the most intriguing question is: why is cannabis capable of altering our consciousness? The answer lies in the endocannabinoid system, an ancient biological network that has existed in animals for 600 million years—we even share it with sea urchins.

A plant that evolved to protect itself from UV rays and herbivores accidentally created a molecule that perfectly fits receptors in our brain. We'll talk about the Scythians and Herodotus, ancient rituals in the Chinese mountains, the secret breeding of cannabis in 20th-century basements, and how humans turned the plant's defense mechanism into a source of pleasure. 

This is a story about how geology shapes biology, and biology shapes culture. 

go to above link for english version


The Life of Earth
https://chuckincardinal.blogspot.com/







Common Cleaning Chemical Could Triple Your Risk of a Dangerous Liver Disease

By SciTechDaily.com, May 18, 2026

Liver fibrosis is a condition in which excessive scar tissue builds up in the liver after repeated injury or inflammation. Over time, this scarring can disrupt normal liver function and may progress to cirrhosis, liver failure, or liver cancer if left untreated. 
Credit: Stock

Scientists are uncovering a possible connection between everyday chemical exposure and serious liver damage.

Most people associate liver disease with heavy drinking or obesity. But researchers are increasingly uncovering another possible threat hiding in everyday life: industrial chemicals that can linger in the air we breathe, the water we drink, and even the clothes we pick up from the dry cleaner.

A new study published in Liver International points to tetrachloroethylene (PCE), a chemical widely used in dry cleaning and manufacturing, as a potential contributor to serious liver damage. Scientists at Keck Medicine of USC found that people with detectable levels of PCE in their blood were more than three times as likely to have significant liver fibrosis, a dangerous buildup of scar tissue that can eventually lead to liver failure, liver cancer, or death.


Tetrachloroethylene (PCE), widely used in dry cleaning and manufacturing, has been linked to increased odds of liver scarring. Credit: Stock



The findings add to growing concerns about how environmental pollutants may quietly influence chronic diseases that are often blamed on lifestyle factors alone. Researchers say the study is the first to directly connect PCE exposure in the general U.S. population with measurable liver scarring.

“This study, the first to examine the association between PCE levels in humans and significant liver fibrosis, underscores the underreported role environmental factors may play in liver health,” said Brian P. Lee, MD, MAS, a hepatologist and liver transplant specialist with Keck Medicine and lead author of the study. “The findings suggest that exposure to PCE may be the reason why one person develops liver disease while someone with the exact same health and demographic profile does not.”


Dr. Brian P. Lee, MD, MAS, is a hepatologist and liver transplant specialist with Keck Medicine of USC and principal investigator of the study. Credit: Dr. Brian P. Lee, MD, MAS



A Chemical Found Far Beyond Dry Cleaning

PCE, also called perchloroethylene, is a colorless volatile organic compound used to dissolve grease and remove stains. Although it is best known as a dry-cleaning solvent, it has also been used in metal degreasing, industrial manufacturing, adhesives, spot removers, and some household cleaning products.

Exposure often happens through inhalation. Clothes cleaned with PCE can slowly release the chemical into indoor air for days after pickup. In some communities, the chemical has also contaminated groundwater and drinking water after industrial spills or improper disposal seeped into the soil. Because PCE evaporates easily, it can spread through buildings and surrounding neighborhoods as a vapor.

Scientists have studied PCE for decades because of its toxic effects. The International Agency for Research on Cancer classifies it as a probable carcinogen, and previous research has linked it to bladder cancer, multiple myeloma, non-Hodgkin lymphoma, and liver cancer. Animal studies have also shown that the chemical can trigger inflammation, oxidative stress, and cellular damage in the liver.

In response to mounting evidence, the U.S. Environmental Protection Agency recently began a 10-year phaseout of PCE in dry cleaning operations and imposed new restrictions on several industrial uses. Still, the compound remains present in some workplaces, consumer products, and older contaminated sites.

Tracking Liver Damage in the U.S. Population

To investigate whether PCE exposure might be affecting liver health on a national scale, researchers analyzed data from the National Health and Nutrition Examination Survey (NHANES), a long-running federal program designed to reflect the health of the U.S. population.

The study included 1,614 adults age 20 and older between 2017 and 2020. Blood testing showed that about 7.4% of participants had detectable levels of PCE. Concentrations ranged from 0.034 to 57.5 nanograms per milliliter.

After adjusting for age, sex, race, ethnicity, education, and other health factors, the connection between PCE and liver fibrosis remained strong. People with detectable PCE exposure had more than triple the odds of significant liver fibrosis compared with those who had no detectable exposure.


PCE can contaminate air and groundwater, creating potential exposure far beyond dry-cleaning shops.
 Credit: Stock



The study also found a striking dose-response relationship: for every one nanogram per milliliter increase in blood PCE concentration (one nanogram is one-billionth of a gram), the odds of significant liver fibrosis increased more than fivefold, with detectable PCE exposure corresponding to an absolute increase in fibrosis risk of nearly 28%.

Importantly, the association appeared independent of traditional liver disease risks such as alcohol use or obesity-related fatty liver disease. That finding raises the possibility that environmental toxins may help explain why some people develop liver disease despite having few conventional risk factors.

“Patients will ask, how can I have liver disease if I don’t drink and I don’t have any of the health conditions typically associated with liver disease, and the answer may be PCE exposure,” said Lee.
Who Faces the Highest Exposure?

The study found that people from higher-income households were more likely to have detectable PCE levels, possibly because they use dry-cleaning services more frequently. However, researchers noted that workers in dry-cleaning facilities and industrial settings may face even greater exposure because of repeated, direct contact with the chemical over long periods.

The authors also performed a “negative control” analysis using a different biomarker linked to mixed VOC exposure. That analysis suggested the liver fibrosis signal was specifically tied to PCE rather than to volatile chemicals in general, strengthening confidence in the findings.
A Growing Focus on Environmental Liver Disease

Liver disease is becoming more common worldwide, and researchers are increasingly exploring how pollution and chemical exposure may contribute alongside diet and alcohol. Unlike smoking or obesity, environmental exposures are often invisible and difficult for individuals to control. Some chemicals can accumulate slowly over years before symptoms appear.

Lee believes the new findings should encourage more research into how environmental toxins affect the liver and whether earlier screening could help identify damage before it becomes irreversible.

“No doubt there are other toxins in our environment besides PCE that are dangerous to the liver,” he said.

He added that recognizing these hidden risk factors could eventually improve patient outcomes.

“We hope our research will help both the public and physicians understand the connection between PCE exposure and significant liver fibrosis,” Lee said. “If more people with PCE exposure are screened for liver fibrosis, the disease can be caught earlier and patients may have a better chance of recovering their liver function.”


The Life of Earth
https://chuckincardinal.blogspot.com/

Scientists Discover “Good” Gut Microbes That Could Protect Against Autism and ADHD

By Cell Press, May 17, 2026

A new study suggests that the gut microbiome and epigenetic “switches” that regulate genes may work together from birth to shape early brain development. 
Credit: Stock

A study found that early-life epigenetic changes and gut microbiome development are closely linked and may shape the risk of ASD and ADHD. Some gut bacteria appeared to offer protective effects against these conditions.

From the moment a baby is born, trillions of microbes begin colonizing the gut while molecular “switches” in the body help control which genes are active.

Now, researchers have found that these two systems, the gut microbiome and epigenetics, may work together in ways that influence early brain development and could shape the risk of neurodevelopmental conditions later in childhood.

The study, published in the journal Cell Press Blue, showed that epigenetic changes present at birth can affect how an infant’s gut microbiome develops during the first year of life. The researchers also identified specific epigenetic patterns and gut microbes linked to signs of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) at age three. Some microbes even appeared to play a protective role, potentially reducing the effects associated with certain epigenetic risk patterns.

“Certain bacteria seem to offer protection, which is exciting because it suggests there could be ways to support a child’s development through diet or probiotics in the future,” says senior author and gastroenterologist Francis Ka Leung Chan of The Chinese University of Hong Kong.

Early childhood is a critical period for both brain development and immune system maturation. While previous studies have shown that epigenetic changes and the infant gut microbiome can each influence long-term health, far less is known about how the two systems interact during the earliest stages of life.

Early-Life Epigenome and Microbiome Interaction

“We wanted to see how the epigenome and microbiome interact in early life and if their interaction could influence a child’s risk of developing neurodevelopmental conditions like ASD and ADHD,” says co-senior author and public health researcher Hein Min Tun of The Chinese University of Hong Kong. “We discovered a kind of conversation happening: a baby’s epigenetic setting at birth can influence their risk for neurodevelopmental disorders, but the presence of certain ‘good’ bacteria in their gut can step in and modify the risk.”

The researchers analyzed DNA methylation patterns, a form of epigenetic change, using umbilical cord blood samples from 571 infants. They combined these findings with gut microbiome data collected from 969 infants at 2, 6, and 12 months of age, as well as samples from the parents during the third trimester of pregnancy.

When the children reached 36 months of age, the team used behavioral questionnaires to evaluate neurodevelopment and explore possible connections between the microbiome, epigenome, and early signs of ASD and ADHD.

The results showed that an infant’s epigenome at birth was linked to factors such as delivery method, gestation length, maternal allergies, and having older siblings. However, it was not influenced by the parents’ gut microbiomes. In contrast, microbiome development was associated with delivery method, antibiotic exposure, breastfeeding, and older siblings. Babies delivered by Cesarean section showed different DNA methylation patterns in genes involved in immune function and brain development.
DNA Methylation Linked to Gut Microbiome Diversity

The researchers also found that epigenetic patterns present at birth affected how the microbiome developed during the first year of life. Infants with higher DNA methylation levels in immune genes related to pathogen recognition tended to have less diverse gut microbiomes by 12 months of age.

The behavioral assessments further showed that signs of ASD and ADHD in 3-year-old children were connected to specific epigenetic markers and certain gut microbes.

Some microbial species appeared to reduce these effects. Infants with epigenetic patterns linked to ASD or ADHD were less likely to show signs of the conditions if they acquired Lachnospira pectinoschiza and Parabacteroides distasonis, respectively, during their first year.

Probiotics and Early Interventions for Neurodevelopment

“The foundations for brain health are laid very early, even before birth,” says Tun. “However, we don’t want people to think this means a child’s developmental path is fixed at birth. These are complex conditions with many causes, and we’ve only uncovered a small piece of a very large puzzle.”

The researchers are continuing to track the children involved in the study to better understand how these early-life factors may influence health later on. They also note that laboratory studies are still needed to confirm the relationship between gut microbes and neurodevelopment.

“The ultimate goal is to develop safe, non-intrusive early interventions such as specific probiotics or live biotherapeutics, that could help nurture a healthy gut microbiome and potentially reduce the risk of neurodevelopmental challenges,” says first author and gastroenterologist Siew Chien Ng of The Chinese University of Hong Kong.


The Life of Earth
https://chuckincardinal.blogspot.com/

Sunday, 17 May 2026

Chuck's picture corner to May 17, 2026

Babies are abounding in the yard, we are finally going to get 3 whole days of above average temps before they once again drop below average for at least a week and who knows beyond that. Fruit trees are beginning to bloom and most shrubs and trees are leafing out. I cut the lawn last week and the next morning had my first signs of allergy symptoms. Ahhh the winter air has also come alive.

the pear tree in bloom behind the cherry tree in bloom taken this morning

 the side yard looking green and alive

I visited Rachelle yesterday, and she has lots of birds visiting her feeders.

A rose breasted grosbeak and I haven't identified the bird on the right.

a purple leafed purple flowering crab, birds enjoy the berries later in the year.

plum blossoms

plum in bloom

I'm putting steel siding up on the house, 10' sheets vertically of black and mid grey in a checkerboard pattern.

what I can reach on the ladder, I'll be putting scaffolding up and have asked for help from the lads the first weekend of July. (any other volunteers would be welcome)

the end of another day.

the first house project of the season begins.

not sure what this weed is.

the white liloc beginning to bloom

It's hard for me to believe I planted these golden weeping willows as cutting a couple of dozen years ago

the clouds of spring

viola

driving home from the grocery store, down the hill on a street facing the river


Enjoy the day
https://chuckincardinal.blogspot.com/

Beyond Pain Relief: Scientists Discover a Protein That Could Stop Osteoarthritis in Its Tracks

By National Research Council of Sci. & Tech., May 16, 2026

Researchers have identified a protein that appears to play a crucial role in protecting cartilage from the damage associated with osteoarthritis, a leading cause of joint pain and reduced mobility worldwide. 
Credit: Stock

Researchers have identified the SHP protein as a key regulator that suppresses cartilage-degrading enzymes and slows osteoarthritis progression.

For millions of people living with osteoarthritis, treatment options have long focused on one thing: managing pain. But while medications and injections may temporarily ease aching knees and stiff fingers, they do little to stop the slow destruction of cartilage that lies at the heart of the disease.

Now, scientists in South Korea say they may have uncovered a powerful new way to protect joints before the damage becomes irreversible.

In a new study published in Nature Communications, researchers identified a protein called SHP (NR0B2) that appears to act as a natural defender of cartilage. The team found that SHP levels decline as osteoarthritis progresses, accelerating joint deterioration. Restoring the protein in animal models not only reduced cartilage damage but also improved joint function and eased pain, raising hopes for therapies that could one day slow or even halt the disease itself.

The research was led by Dr. Chul-Ho Lee and Dr. Yong-Hoon Kim at the Laboratory Animal Resource Center of the Korea Research Institute of Bioscience and Biotechnology (KRIBB), in collaboration with Prof. JinHyun Kim at Chungnam National University Hospital.


From left: Kang Eun-jeong, researcher, and Lee Chul-ho and Kim Yong-hoon, principal researchers at KRIBB. 
Credit: KRIBB



SHP protects vulnerable cartilage

To investigate SHP’s role, the researchers analyzed cartilage tissue from osteoarthritis patients as well as animal models of the disease. They discovered that SHP protein levels dropped sharply as osteoarthritis advanced, suggesting that the loss of this protective molecule may contribute directly to cartilage breakdown.

Further experiments revealed just how important the protein may be. Mice lacking SHP developed more severe pain and experienced faster cartilage degeneration than normal mice. In contrast, restoring SHP levels in affected joints significantly reduced cartilage damage and improved mobility, highlighting the protein’s potential as a therapeutic target.
A pathway slows cartilage breakdown

The mechanistic work showed that SHP helps defend cartilage by reducing the production of enzymes that destroy the tissue, especially MMP-3 and MMP-13.

These enzymes are known to break down cartilage. For the first time, the researchers showed that SHP blocks these enzymes at the signaling level by controlling the IKKβ/NF-κB pathway, helping preserve cartilage structure.

Schematic illustration of SHP (NR0B2)-mediated protection against osteoarthritis.
 Credit: Korea Research Institute of Bioscience and Biotechnology (KRIBB)

Gene delivery reduces damage

The team then tested whether SHP could be used therapeutically through gene delivery. After injecting a viral vector carrying the SHP gene into affected joints, the researchers observed lasting benefits from a single treatment.

Even in animals that already had osteoarthritis, the approach significantly reduced cartilage damage and relieved pain.

“This study is the first to demonstrate that the SHP protein plays a critical role in protecting cartilage during the development and progression of osteoarthritis,” said Dr. Chul-Ho Lee, the study’s lead investigator. “Therapeutic strategies targeting SHP may offer a new approach to slowing or preventing osteoarthritis progression.”


The Life of Earth
https://chuckincardinal.blogspot.com/

Ancient Roman Technique Discovered 8,000 Years Earlier, Study Says

17 May 2026, By R. McLendon

Interior of the Pantheon, Rome.
 (Francesco Riccardo Iacomino/Moment/Getty Images)

The Roman Empire helped transform humanity for centuries during its reign, then left a legacy that has continued to influence civilization ever since.

Even the ancient Romans had to stand on giants' shoulders, though.

That includes not just earlier civilizations like Egypt and Greece, but also countless prehistoric people whose innovations have been largely lost to history – or, in some cases, erroneously attributed to later generations.

In a new study, researchers report that a sophisticated plaster-making technique long credited to the Romans was also used by Neolithic people about 8,000 years earlier.

But how is that possible?

Ancient Rome is renowned for its engineering prowess, as seen in iconic projects like the aqueducts and the Pantheon. In addition to their design and construction skills, Roman builders likely benefitted from durable concrete and other high-quality materials.

Some Roman buildings incorporated dolomite-based plaster, a quick-drying paste, which is stronger and more water-resistant than the traditional calcitic plasters often produced in antiquity.

"However, using dolomitic lime is challenging and requires a high level of expertise at all steps of preparation, which may explain why it is not commonly found in archaeological sites," the researchers write.

Dolomite refers to a mineral made of calcium magnesium carbonate, or to a rock featuring mostly this mineral. Similar to calcitic limestone, it can serve as a source of the inorganic material lime, which in turn can be useful in the production of certain building materials.

The earliest written record of dolomitic lime seems to come from the Roman architect and engineer Vitruvius during the first century BCE, the authors note.

While Vitruvius didn't mention dolomite by name, he seemed to describe the mineral in a discussion of lime production.

Plaster had been common for a long time before Vitruvius, but there is little indication of anyone using dolomitic lime before his description of it about 2,000 years ago.

Archaeological evidence suggests the main materials for making plaster in prehistory were calcite and gypsum.

About 10,000 years ago, however, people at a Neolithic settlement in the Judean Hills apparently made dolomite-based plaster, leaving behind subtle clues that went unnoticed until now, the researchers report.

Located in what's now Israel and Palestine, this region was already a hub of human activity at the time, bustling with settlements thousands of years before the dawn of the Iron Age or the Roman Empire.

An overview of the Motza archaeological site.
 (Maor et al., J. Archaeol. Sci., 2026)

One of those settlements eventually became the modern-day archaeological site known as Motza, located about 5 kilometers west of Jerusalem, where researchers conducted a series of excavations between 2015 and 2021 before construction of a highway through the area.

Sifting through multiple occupations over the millennia, the researchers focused on a large Neolithic settlement dated to roughly 9,000 years ago. They found more than 100 plaster floors from that era, noting many were "particularly well-preserved and coated with red pigment".

They also found separate kilns where residents had burned either limestone or dolomite to make plaster, indicating a degree of sophistication not often attributed to Neolithic people.

Calcitic and dolomitic lime require different conditions for plaster production, the researchers explain, and yet these prehistoric people evidently understood that well enough to build specialized kilns for each substance.

Using dolomite to make plaster was an impressive feat for humans at the time, but the method employed at Motza remains intriguing even by modern standards, the researchers add.

"They may have successfully made dolomitic plaster where dolomite is fully recrystallized along with the calcite, something that to our knowledge has not been observed anywhere else and was thought to be physically impossible," they write.

Aside from capitalizing on a local abundance of dolomite, this method likely yielded a superior plaster for use in buildings, with greater strength and water resistance than traditional alternatives.

Given the difficulty of making dolomite-based plaster, plus the lack of earlier evidence, credit for its invention has long fallen to Ancient Rome.

While it's possible the technique survived for 8,000 years after Motza and then resurfaced in Rome, the lack of archaeological evidence from the interim seems to indicate the Romans independently discovered it.

"The results suggest a technology lost to history," the researchers write.


The birth of modern Man
https://chuckincardinal.blogspot.com/

Saturday, 16 May 2026

Mysterious Wall Stone Turned Out to Be an Unexpected Treasure

16 May 2026, By M. Starr

You don't see that every day. 
(Hart et al., J. Vertebr. Paleontol., 2023)

It all started with a simple landscaping project.

Retired chicken farmer Mihail Mihailidis just wanted to build a retaining wall. He acquired a block of sandstone from a local quarry in Kincumber, Australia, and set to work preparing it for its new purpose.

When he turned the stone over, however, his plans fell apart.

There, clear as daylight, was an unmistakable impression of an ancient creature. The outline was so distinct that even a non-expert could tell it wasn't just an odd pattern in the rock. Something had been preserved there – something with a spine, limbs, and a body that had once moved through water.


Meet Arenaerpeton supinatus, a name that means "upside-down sand-creeper".
 (UNSW Sydney/Richard Freeman)



In 2023, decades after the Mihailidis family donated the stone to the Australian Museum, scientists formally described the beastie, named Arenaerpeton supinatus. It's a rare, extinct relative of modern amphibians, belonging to a group known as temnospondyls, and it lived hundreds of millions of years ago.

It's similar to a prehistoric salamander, but chunkier, and with a nastier set of teeth.

"Superficially, Arenaerpeton looks a lot like the modern Chinese Giant Salamander, especially in the shape of its head," said paleontologist Lachlan Hart of the University of New South Wales (UNSW) and the Australian Museum.

"However, from the size of the ribs and the soft tissue outline preserved on the fossil, we can see that it was considerably more heavyset than its living descendants. It also had some pretty gnarly teeth, including a pair of fang-like tusks on the roof of its mouth."


An artist's impression of Arenaerpeton in life. 
(Jose Vitor Silva)



The fossil truly is a spectacular specimen. It's preserved in sandstone, which is interesting enough.

Sandstone often preserves ancient traces, but it typically forms in dynamic, oxygen-rich environments where bodies are easily broken apart and decompose quickly.

In most cases, that means only fragments, such as isolated bones, teeth, or tracks, survive long enough to fossilize. Complete skeletons are much harder to come by, and delicate features like skin or body outlines almost never make it through the process intact.

Arenaerpeton – the only specimen of its species ever found – is very far from the typical sandstone fossil. The skeleton is almost complete and fully articulated, and the fossil retains traces of soft tissue – rare in any fossil, let alone sandstone.


The fossil (A) and a diagram (B) of the articulated skeleton of Arenaerpeton.
 (Hart et al., J. Vertebr. Paleontol., 2023)



"This is one of the most important fossils found in New South Wales in the past 30 years, so it is exciting to formally describe it," said paleontologist Matthew McCurry of UNSW and the Australian Museum.

"It represents a key part of Australia's fossil heritage."

The researchers believe that Arenaerpeton died in a calm aquatic environment with anoxic or colder bottom waters, inhospitable to scavengers, where its carcass could lie undisturbed while fossilization processes unfolded.

With little disruption and limited oxygen, decay slowed to a crawl, giving the surrounding sediment time to seal in the shape of the animal's body before it could disintegrate.


Arenaerpeton's cranium and mandible. 
(Hart et al., J. Vertebr. Paleontol., 2023)



"We don't often find skeletons with the head and body still attached," Hart said, "and the soft tissue preservation is an even rarer occurrence."

The animal dates back around 240 million years, to the Triassic period – a time before dinosaurs rose to dominance, when the world was still recovering from the Great Dying, the most devastating extinction event the world has ever seen.

During this time, Australia was still part of the Gondwana supercontinent and sat closer to the South Pole than it does today. Temnospondyls were relatively widespread across Gondwana, and their remains have been found across multiple continents that later split apart.

Arenaerpeton inhabited freshwater rivers in a region now known as the Sydney Basin and likely hunted fish with its fearsome tusks.

The specimen is missing its tail, but Hart estimates its full length was around 1.2 meters (3.9 feet). That's toward the larger end for early temnospondyls in Australia, although some later relatives would grow significantly bigger.

This size could have given it a leg up the evolutionary ladder.

"The last of the temnospondyls were in Australia 120 million years after Arenaerpeton, and some grew to massive sizes," Hart explained.

"The fossil record of temnospondyls spans across two mass extinction events, so perhaps this evolution of increased size aided in their longevity."

Arenaerpeton spent decades languishing in storage before arriving at its rightful place in the fossil record – a missing link that may help explain the rise of the temnospondyls.

So maybe take a leaf out of Mihailidis's book and give a closer look to that slab of rock before adding it to your garden wall.


The Life of Earth
https://chuckincardinal.blogspot.com/