Thursday, 31 July 2025

Even a slight slowdown of key Atlantic currents poses a 'stunning risk' to rainforests

By Ben Turner published July 30, 2025

The Amazon River flows for more than 4,100 miles (6,600 km); within its hundreds of tributaries and streams are the largest number of freshwater fish species in the world.
 (Image credit: DeAgostini via Getty Images)

A slowing Atlantic current could have a devastating impact on the planet's rainforests, a new study warns.

Even a small slowdown to one of Earth's major ocean currents could nearly halve the rainfall over parts of the planet's rainforests, fueling droughts that could accelerate climate change, a new study warns.

The Atlantic Meridional Overturning Circulation (AMOC), which includes the Gulf Stream, plays a key stabilizing role in climates around the planet. Yet a number of studies indicate that the current is slowing, with some even suggesting its heading toward a disastrous collapse.

Now, a new study has analyzed 17,000-year-old climate records to connect the current's weakening with its effects on the planet's tropics. Published Wednesday (July 30) in the journal Nature, the research suggests that the possible impact presents "a stunning risk" that could send swathes of usually humid regions, in the Amazon rainforest and elsewhere, into drought.

"This is bad news, because we have these very important ecosystems in the Amazon," study lead author Pedro DiNezio, an atmospheric and ocean scientist at the University of Colorado Boulder, said in a statement. "The Amazon rainforest contains almost two years of global carbon emissions, making it a major carbon sink on Earth. Drought in this region could release vast amounts of carbon back into the atmosphere, forming a vicious loop that could make climate change worse."

The AMOC acts as a planetary conveyor belt, bringing nutrients, oxygen and heat north from tropical waters while moving colder water south — a balancing act that keeps both sides of the Atlantic 9 degrees Fahrenheit (5 degrees Celsius) warmer than it would otherwise be.

But research into Earth's climate history shows that the current has switched off in the past, and some studies have hinted that glacial meltwater released by climate change is causing the AMOC to slow. The worst-case scenarios predicted by some models suggest that the current may outright collapse sometime this century, leading to devastating and irreversible impacts felt across the globe.

These predictions remain controversial, yet the risks are large enough for scientists to have called for urgent investigation. The effects of a diminished AMOC would include plummeting temperatures in Europe and storms proliferating around the equator — but scientists have also pointed to other, less foreseeable, impacts in Earth's tropical regions.

To investigate these possible outcomes, the researchers behind the new study pooled data of ancient rainfall patterns preserved in cave formations and lake and ocean sediments. They then plugged them into climate models to simulate the shifts in the past and how they may change in the future.

These models predict that a weakening AMOC would cool the northern Atlantic, causing temperatures to drop in the tropical Atlantic and Caribbean. This change, accompanied by rising global temperatures due to climate change, would lead to a drop in precipitation over regions in the rainforest belt, with rainfall dropping by up to 40% over parts of the Amazon rainforest.

Yet despite this alarming prediction, the researchers stress that the situation isn't hopeless: Though the tropics may remain sensitive to small shifts in the AMOC's strength, they say it is unlikely to collapse completely.

The fate of the current, and how severely it slows, depends on tackling climate change now.

"We still have time, but we need to rapidly decarbonize the economy and make green technologies widely available to everyone in the world," DiNezio said. "The best way to get out of a hole is to stop digging."



The Life of Earth
https://chuckincardinal.blogspot.com/

World's Longest Lightning Strike Crossed 515 Miles From Texas to Kansas

31 July 2025, By M. STARR

Animation based on data for the world's longest lightning flash. 
(Georgia Tech Research Institute)

A bolt of lightning that arced across the sky from Texas to Kansas in the fall of 2017 has officially smashed the record for the world's longest.

During a major thunderstorm in October 2017, the colossal crack of jagged electricity streaked across the Great Plains of North America for 829 kilometers (515 miles) – a distance that surpassed the previous record by 61 kilometers.

"We call it megaflash lightning and we're just now figuring out the mechanics of how and why it occurs," says geographical scientist Randy Cerveny of Arizona State University and the World Meteorological Organization.

"It is likely that even greater extremes still exist, and that we will be able to observe them as additional high-quality lightning measurements accumulate over time."

Lightning is one of the most breathtaking phenomena on Earth. It occurs when turbulent conditions in the atmosphere jostle particles around, rubbing them together to generate charge. Eventually, so much charge builds up that it has to go somewhere, producing a discharge of millions of volts across the sky.

The lightning bolt with the previously greatest-known horizontal distance was recorded on 29 April 2020, when a cloud-to-cloud megaflash covered a distance of 768 kilometers across parts of Texas, Louisiana, and Mississippi.

Both the previous and current record-holders were detected using the NOAA's GOES-16 and GOES-17 geostationary weather satellites, which are equipped with Geostationary Lightning Mappers (GLMs) that continuously monitor the sky for extreme lightning.


The flash traveled almost throughout the entire cloud.
 (Michael Peterson/GTRI)



GOES-16 was launched in late 2016, and managed to record the giant storm of October 2017, but the megaflash wasn't detected until a team led by atmospheric scientist Michael Peterson of Georgia Institute of Technology's Severe Storms Research Center revisited the data.

Most lightning bolts are relatively small, less than 10 miles long, and have a tendency to strike vertically. But some travel horizontally through the clouds, and if the cloud complex is particularly large, that can mean giant bolts of lightning. Anything more than 100 kilometers long is considered a megaflash.

Measuring a megaflash is painstaking work that involves putting together satellite and ground-based data to reconstruct the extent of the event in three dimensions. This helps determine that the megaflash is one single lightning strike, as well as measuring just how big it is. Because the strike is often at least partially obscured by cloud, such megaflashes are easy to miss.

The GOES satellites are a major part of the puzzle, since they continuously monitor the sky. They also identified the longest-lasting lightning strike on record back in 2022, a colossal flash that lasted 17.102 seconds during a storm over Uruguay and Argentina in June 2020.


Composite satellite imagery shows the development of the flash over time, with red and blue symbols showing where ground strikes occurred. 
(Michael Peterson/GTRI)



It's no coincidence that both megaflashes occurred over the Great Plains. This region is a major hotspot for the mesoscale convective system thunderstorms that are most conducive to megaflashes. So, if the record is to be broken in the future – which is a strong possibility – it could come from the same region.


"The extremes of what lightning is capable of is difficult to study because it pushes the boundaries of what we can practically observe. Adding continuous measurements from geostationary orbit was a major advance," says Peterson.

"We are now at a point where most of the global megaflash hotspots are covered by a geostationary satellite, and data processing techniques have improved to properly represent flashes in the vast quantity of observational data at all scales.

"Over time, as the data record continues to expand, we will be able to observe even the rarest types of extreme lightning on Earth and investigate the broad impacts of lightning on society," Peterson concludes.



The Life of Earth
https://chuckincardinal.blogspot.com/

This Virus Doesn’t Make You Sick. It Makes You Stronger

BY U. OF CALIFORNIA - SAN DIEGO, JULY 30, 2025

A common plant virus awakens the immune system to fight cancer—and it’s grown using sunlight, soil, and science. 
Credit: Shutterstock

A virus normally found in black-eyed peas is emerging as a powerful ally in the fight against cancer.

Scientists discovered that this plant virus, called CPMV, doesn’t infect human cells—but it does trigger a potent immune response, training the body to recognize and destroy cancer cells. Unlike typical therapies, it primes both innate and adaptive immunity, offering long-term protection.

Plant Virus Shows Promise as Cancer Immunotherapy

A virus known for infecting black-eyed peas is now emerging as a surprisingly powerful tool in cancer treatment, and scientists are beginning to understand why.

Researchers from the University of California San Diego, led by a team of chemical and nano engineers, recently published a study in Cell Biomaterials that dives into how the cowpea mosaic virus (CPMV) stimulates the human immune system in a way that other plant viruses do not. Unlike its viral relatives, CPMV appears to uniquely trigger immune cells to recognize and fight cancer.

Immune System Activation and Anti-Tumor Memory

In laboratory studies involving mice and even dogs with cancer, CPMV has shown strong anti-tumor effects. When injected directly into a tumor, the virus draws various innate immune cells into the area, including neutrophils, macrophages, and natural killer cells, which begin attacking the cancer. At the same time, CPMV activates B cells and T cells to build a long-term immune memory. This response not only helps eliminate the original tumor but also prepares the immune system to find and attack cancer that may have spread elsewhere in the body.

“It is fascinating that CPMV but not other plant viruses stimulates an anti-tumor response,” said Nicole Steinmetz, the Leo and Trude Szilard Chancellor’s Endowed Chair in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at the UC San Diego Jacobs School of Engineering and the study’s corresponding author.

“This work gives us insight into how CPMV works so well,” said study first author Anthony Omole, a chemical and nano engineering Ph.D. student in Steinmetz’s lab. “What we found most exciting is that although human immune cells are not infected by CPMV, they respond to it and are reprogrammed towards an activated state, which ultimately trains them to detect and eradicate cancerous cells.”
What Makes CPMV Unique? A Side-by-Side Viral Comparison

A key question in translating CPMV to human cancer patients has been: what makes this plant virus so effective at fighting cancer?

To investigate, Omole, Steinmetz, and colleagues at the National Cancer Institute’s ​​Nanotechnology Characterization Laboratory performed a side-by-side comparison of CPMV with the cowpea chlorotic mottle virus (CCMV), a closely related plant virus that does not exhibit anti-tumor effects when administered intratumorally. Both viruses form similarly sized nanoparticles and are taken up by human immune cells at similar rates. Yet, once inside, the viruses produce different outcomes.


Side-by-side illustration of the cowpea mosaic virus (CPMV, left), which has potent cancer-fighting effects, and the closely related cowpea chlorotic virus (CCMV, right), which does not exhibit anti-tumor effects. 
Credit: Anthony Omole



Viral RNA Processing and Immune Signaling

CPMV, the team found, stimulates type I, II and III interferons—proteins with well-known anti-cancer properties. “This is particularly interesting because some of the earliest cancer immunotherapy drugs were recombinant interferons,” noted Omole. Meanwhile, CCMV stimulates a set of pro-inflammatory interleukins that do not translate to effective tumor clearance.

Another difference lies in how these viruses’ RNAs are processed within mammalian cells. CPMV RNAs persist longer and get delivered to the endolysosome, where they activate toll-like receptor 7 (TLR7), a critical component in priming antiviral—and more importantly—anti-tumor immune responses. CCMV RNAs, on the other hand, fail to reach this activation point.

A Cheap, Scalable Therapy Grown in Plants

CPMV also offers a unique advantage as a cost-effective immunotherapy. Unlike many other therapies that require complex and costly manufacturing, CPMV can be produced using molecular farming. “It can be grown in plants using sunlight, soil, and water,” Omole said.

The team is working toward advancing CPMV to clinical trials.

“The present study provides important insights into the mechanism of action of CPMV. We are diligently working toward the next steps to ensure that the most potent lead candidate is selected to achieve anti-tumor efficacy and safety,” Steinmetz said. “This is the time, and we are poised to move this work beyond the bench and toward clinical trials.”



The Life of Earth
https://chuckincardinal.blogspot.com/

Wednesday, 30 July 2025

Chuck's photo corner to July 30, 2025

A hot, humid, sunny week as the dog days of summer begins. I got to water today, the gardens are so dry. Forecasters once again promised rain for the day today, and this morning has once again evaporated.

a zinnia grown from seed has finally managed to bloom despite it ultra dry location near the road

sunset on the ferry, on the way home from a summer barbeque

day is done



the mini rose, from Valentines, planted at Rachelle's





Russian sage, enjoying this years hot dry summer.

The last daylily variety to bloom.

Red dahlias handed down in the family for generations given to me by a dear friend

Chili on the way.

second last daylily variety to blossom

plum tomatoes 

Bacon and tomato coming soon my dear gut, lol



Enjoy
https://chuckincardinal.blogspot.com/

The Shocking Way Your Lettuce Might Be Getting Contaminated

BY CORNELL U. , JULY 29, 2025


Contaminated irrigation and inadequate cold storage are fueling E. coli in lettuce. But the fix? It’s simpler—and more effective—than you might think. 
Credit: Shutterstock



Romaine lettuce has been linked to repeated E. coli outbreaks, but new research from Cornell University uncovers how contamination happens—and how to stop it.

The study highlights irrigation water, especially untreated surface water applied through spray systems, as a key culprit. Switching to drip or furrow irrigation and improving cold storage during transport can drastically reduce risk. The research urges a systems-wide rethink, showing how smarter farming and better logistics—from the field to the fridge—can prevent outbreaks and boost food safety.
E. coli in Romaine: A Persistent Threat

E. coli outbreaks linked to romaine lettuce have remained a persistent public health issue. New research from Cornell University highlights that a combination of on-farm strategies and post-harvest handling methods could significantly reduce the risk to consumers.

The study was co-authored by Renata Ivanek, a professor in population medicine and diagnostic sciences, and Martin Wiedmann, a food safety professor. Their findings emphasize practical steps that could meaningfully enhance the safety of romaine lettuce grown and sold in the United States.
Key Risks: Irrigation Water and Contamination

“This study supports that interventions should focus on reducing produce contamination via contaminated irrigation water, on assuring that produce washes applied during processing consistently deliver reasonably high reductions of bacterial numbers, and on improving temperature control during distribution,” Wiedmann said.

“We tried to describe the system as holistically as possible to account for different risk factors and how they could have interactions,” Ivanek said. “There’s not just one intervention that will save us all. We spent a lot of time trying to understand the preharvest component, especially the irrigation water piece, and how much risk can be explained by that.”

Spraying lettuce with untreated water may look routine, but it’s a major contamination risk. Scientists now urge growers to rethink irrigation practices to help prevent future E. coli outbreaks.
 Credit: Shutterstock

Irrigation Methods Make a Big Difference

The study found that a large portion of contamination stems from the use of untreated surface water delivered through overhead spray irrigation. The researchers observed that switching to treated water or using alternative irrigation systems, such as furrow or drip irrigation, significantly reduced the risk.

“While not the most common system, spray irrigation is used in a number of fields for its benefits during germination, its cooling effect on plants, and other reasons. But drip or furrow irrigation reduces the probability that water directly touches the leaves,” Ivanek said, acknowledging that switching to these other irrigation systems introduces significant potential additional costs to the grower.

The Cold Chain’s Crucial Role

Ivanek and her co-authors also explored the importance of maintaining proper cold storage temperatures along the entire supply chain to romaine’s final destination.

“Time and temperature play a role in food safety, and also in food quality and shelf life,” she said, describing a “perfect storm” if contamination happens at the farm or processing level and then improper transportation temperatures allow bacteria to grow.

The comprehensive practices and interventions explored in this study intend to aid decision-makers in establishing and enhancing food safety best management practices, Ivanek said.

America’s Food Supply: Safe, but There’s Room to Improve

“The big message is the American food supply chain is extremely safe compared to other countries,” she said. “We’re exploring how we can make it even safer and where we should put additional effort.”



The Life of Earth
https://chuckincardinal.blogspot.com/

Google has turned 2 billion smartphones into a global earthquake warning system — it's as effective as seismometers, tests show

By Ben Turner published July 30, 2025
https://www.livescience.com/technology/communications/google-has-turned-2-billion-smartphones-into-a-global-earthquake-warning-system-its-as-effective-as-seismometers-tests-show

Fire fighters conduct search and rescue operations among collapsed buildings in Hualien, Taiwan in 2024. 
(Image credit: Ministry of Interior / Handout /Anadolu via Getty Images)

Google's earthquake early-warning system has used phone accelerometers on Android devices to increase quake alerts by tenfold across 98 countries.

Google has harnessed motion sensors on more than 2 billion smartphones to create an earthquake early-warning system that's as effective as standard seismometers, a new study reveals.

Between 2021 and 2024, the company's Android Earthquake Alerts (AEA) system captured more than 11,000 quakes through smartphone accelerometers and issued more than 1,200 alerts to Android users across 98 countries.

This system has led to a tenfold increase in the number of people with access to earthquake alerts, from 250 million in 2019 to 2.5 billion today. The researchers published their findings July 17 in the journal Science.

"Earthquakes are a constant threat to communities around the globe. While we've gotten good at knowing where they're likely to strike, we still face devastating consequences when they do," Google representatives wrote in a statement. "What if we could give people a few precious seconds of warning before the shaking starts? Those seconds can be enough time to get off a ladder, move away from dangerous objects and take cover."

In recent decades, earthquake alert systems have been rolled out in countries such as China, Mexico, Japan, South Korea and the United States. Yet these systems, built using seismic stations as nodes, are expensive, meaning that most earthquake-prone countries have only regional coverage and many others have none.

To fill this coverage gap, the Google researchers designed the AEA system to use smartphone and smartwatch accelerometers to detect fast-moving P-waves, which typically precede more destructive S-waves during an earthquake. Using this sensor network, AEA can estimate the size of an earthquake and where it will hit, and then send warnings to users in the danger zone.

Breaking new ground

The researchers faced many challenges. Phone accelerometers are far less accurate than seismometers, so the team pieced together data from the sheer ubiquity of Android devices and their default logging of motion data.

Transforming these pooled signals into meaningful warnings required them to account for differences between devices and regional variations in geology and building layouts.

Now operating in several countries — including Greece, Turkey, the United States, Japan and Indonesia — the AEA had issued 1,279 alerts as of March 2024.

User feedback reveals that 85% of people who experienced an earthquake received an alert, with 36% getting one before the shaking started, 28% during and 23% after.

Only three of the alerts were false, with two being triggered by thunderstorms and another by an unrelated mass notification event that vibrated a number of phones.

But issues remain, especially in estimating the magnitude of large quakes, such as those that hit Turkey in February 2023. These tremors were significantly underestimated by the AEA, which the researchers attributed to flaws in algorithms and collection methods that they have since updated.

Events like this raise questions about lifesaving software being owned and operated by a tech giant, but Google insists its technology will merely "help supplement official warning systems" instead of replacing them.

"AEA demonstrates that globally distributed smartphones can be used to detect earthquakes and issue warnings at scale with an effectiveness comparable to established national systems," the researchers wrote in the study. "Large earthquakes remain the most important and challenging for all EEW [earthquake early-warning] systems, and the global implementation of AEA supports efforts to improve detection with rapid, large-scale data collection and feedback to algorithms."



The Birth of modern Man
https://chuckincardinal.blogspot.com/

Tuesday, 29 July 2025

No GMOs, No Chemicals – Just a Fungus Making Bread Better for You

BY WILEY, JULY 28, 2025

A tiny fungus in the soil helps wheat grow bigger, more nutritious grains—no chemicals needed. 
Credit: Shutterstock

Scientists have discovered that a common soil fungus, Rhizophagus irregularis, can naturally boost the nutritional value of bread wheat.

When wheat is grown with this fungus, the grains become larger and richer in essential micronutrients like zinc and phosphorus. Even better, the added phosphorus doesn’t increase phytate—an anti-nutrient that blocks mineral absorption—so the nutrients remain more available to the body. This finding could lead to more nutritious, naturally fortified wheat without needing chemical additives or genetic modification.

Fungi as Natural Micronutrient Boosters

A study published in Plants, People, Planet has found that growing bread wheat alongside a particular soil fungus can naturally enhance the grain’s nutrient content.

Researchers compared wheat grown with and without the arbuscular mycorrhizal fungus Rhizophagus irregularis. They discovered that wheat paired with the fungus produced larger grains containing more phosphorus and zinc. Importantly, the increased phosphorus levels did not lead to a rise in phytate (a compound known to reduce the body’s ability to absorb zinc and iron). This means that wheat grown with the fungus offered more bioavailable zinc and iron than wheat grown without it.
A Sustainable Path to Biofortified Wheat

“Beneficial soil fungi could be used as a sustainable option to exploit soil-derived plant nutrients. In this case, we found potential to biofortify wheat with important human micronutrients by inoculating the plants with mycorrhizal fungi,” said corresponding author Stephanie J. Watts-Williams, PhD, of the University of Adelaide, in Australia.



The Life of Earth
https://chuckincardinal.blogspot.com/

11,000-Year-Old Dinner Party: Why Neolithic People Hauled Wild Boars Across Mountains

BY AUSTRALIAN NATIONAL U. , JULY 28, 2025

Samples of ancient boar teeth unearthed at the archaeological site of Asiab in the Zagros Mountains. Credit: Nic Vevers/ANU

Prehistoric communities in western Iran brought wild boars from far distances as symbolic gifts for a communal feast.

While magnets and shot glasses make for lighthearted holiday keepsakes, food items deeply tied to a country’s culture often hold greater sentimental value. Examples include French cheese, Dutch Stroopwafels, and Canadian maple syrup—gifts that speak to a place’s identity.

Recent research reveals that this idea of meaningful food gifting isn’t just modern. Around 11,000 years ago, during the Early Neolithic period, communities living in what is now western Iran embraced a similar tradition.

These early societies put considerable effort into hunting wild boars from scattered regions across the landscape. They then transported the animals to a communal feast held at the site now known as Asiab, located in the Zagros Mountains.

The study, carried out by an international team of scientists that included researchers from The Australian National University (ANU), shows that the concept of sharing foods with geographic significance during social gatherings has roots that stretch deep into human prehistory.
Culinary Traditions and Social Bonds

“Food and long-standing culinary traditions form an integral component of cultures all over the globe. It is for this reason holidays, festivals, and other socially meaningful events commonly involve food. For example, we cannot imagine Christmas without the Christmas meal, Eid without the food gifts, or Passover without matzo ball soup,” Dr Petra Vaiglova from ANU said.

The scientists unearthed the skulls of 19 wild boars that were neatly packed and sealed inside a pit within a round building at the Asiab site. Butchery marks on the animals’ skulls suggest they were used for feasting, but until now scientists were unsure where these boars came from.

Communities arriving at the Early Neolithic site of Asiab with wild boar for a communal feast. 
Credit: Kathryn Killackey

Dr Vaiglova and the international research team examined the tooth enamel of five of these wild boars. The researchers analyzed microscopic growth patterns and chemical signatures inside the enamel that offered “tell-tale” signs indicating that at least some of the boars used for the feast were not from the area where the gathering took place.

“Just like trees and their annual growth rings, teeth deposit visible layers of enamel and dentine during growth that we can count under the microscope. This is the first time these growth layers have been used to guide geochemical analysis of animal teeth to answer questions about human-animal interactions,” Dr Vaiglova said.

“Rainfall and bedrock have distinct isotopic values in different geographical locations. These isotopic values get incorporated into animal tissues through drinking water and food. Measuring the isotopic values of tooth enamel allowed us to assess whether all the animals came from the same part of the region or whether they originated from more dispersed locations.

Surprising Distances and Symbolic Meaning

“Because the values we measured across the five teeth showed a high amount of variability, it is unlikely that all the animals originated from the same location. It is possible that some of them originated roughly 70 kilometers away from the site where the feast took place.”

The researchers said it is surprising that these hunters went through such effort to kill and transport boars from their local region over difficult mountainous terrain during a journey that likely would have taken several days, especially considering boars were not the most hunted animal during the Early Neolithic period.

Dr Vaiglova said communities living in the Zagros Mountains at this time had a “very diverse hunting strategy” and were hunting lots of different animal species.

“Boars are especially aggressive and so displaying them as hunting trophies or presenting them at a feast carries with it a certain element of significance. Bringing these animals from distant locations would have undoubtedly helped celebrate the importance of the social event that took place at Asiab,” she said.

“What is special about the feast at Asiab is not only its early date and that it brought together people from across the wider region, but also the fact that people who participated in this feast invested substantial amounts of effort to ensure that their contributions involved an element of geographic symbolism. This feast also took place at a time that pre-dates agriculture and farming practices.

“This was clearly a very meaningful event, and the fact that people put in so much effort to transport the boars over such challenging terrain provides us with a glimpse of how old the tradition of bringing geographically meaningful gifts to social events really is.

“These people were clearly the ultimate dinner party guests.”




The birth of modern Man
https://chuckincardinal.blogspot.com/


Stomach-Churning Theory Could Explain Mystery of Neanderthal Diet

28 July 2025, By M. BEASLEY, THE CONVERSATION
https://www.sciencealert.com/stomach-churning-theory-could-explain-mystery-of-neanderthal-diet

(gorodenkoff/Getty Images)

Scientists long thought that Neanderthals were avid meat eaters. Based on chemical analysis of Neanderthal remains, it seemed like they'd been feasting on as much meat as apex predators such as lions and hyenas.

But as a group, hominins – that's Neanderthals, our species and other extinct close relatives – aren't specialized flesh eaters. Rather, they're more omnivorous, eating plenty of plant foods, too.

It is possible for humans to subsist on a very carnivorous diet. In fact, many traditional northern hunter–gatherers such as the Inuit subsisted mostly on animal foods.

But hominins simply cannot tolerate consuming the high levels of protein that large predators can. If humans eat as much protein as hypercarnivores do over long periods without consuming enough other nutrients, it can lead to protein poisoning – a debilitating, even lethal condition historically known as "rabbit starvation."

So, what could explain the chemical signatures found in Neanderthal bones that seem to suggest they were healthily eating tons of meat?

I am an anthropologist who uses elements such as nitrogen to study the diets of our very ancient ancestors. New research my colleagues and I conducted suggests a secret ingredient in the Neanderthal diet that might explain what was going on: maggots.


A black soldier fly adult. The larvae of this fly are one of the species of maggots studied. (blacksoldierflyblog.com/Wikimedia commons/CC BY SA 3.0)


Isotope ratios reveal what an animal ate

The ratios of various elements in the bones of animals can provide insights into what they ate while alive. Isotopes are alternate forms of the same element that have slightly different masses.

Nitrogen has two stable isotopes: nitrogen-14, the more abundant form, and nitrogen-15, the heavier, less common form. Scientists denote the ratio of nitrogen-15 to nitrogen-14 as δ¹⁵N and measure it in a unit called permil.

As you go higher up the food chain, organisms have relatively more of the isotope nitrogen-15. Grass, for example, has a very low δ¹⁵N value. An herbivore accumulates the nitrogen-15 that it consumes eating grass, so its own body has a slightly higher δ¹⁵N value.

Meat-eating animals have the highest nitrogen ratio in a food web; the nitrogen-15 from their prey concentrates in their bodies.

By analyzing stable nitrogen isotope ratios, we can reconstruct the diets of Neanderthals and early Homo sapiens during the late Pleistocene, which ran from 11,700 to 129,000 years ago.


Fossils from various sites tell the same story – these hominins have high δ¹⁵N values. High δ¹⁵N values would typically place them at the top of the food web, together with hypercarnivores such as cave lions and hyenas, whose diet is more than 70% meat.

But maybe something else about their diet was inflating Neanderthals' δ¹⁵N values.

Uncovering the Neanderthal menu

We suspected that maggots could have been a different potential source of enriched nitrogen-15 in the Neanderthal diet. Maggots, which are fly larvae, can be a fat-rich source of food. They are unavoidable after you kill another animal, easily collectible in large numbers and nutritionally beneficial.

To investigate this possibility, we used a dataset that was originally created for a very different purpose: a forensic anthropology project focused on how nitrogen might help estimate time since death.

I had originally collected modern muscle tissue samples and associated maggots at the Forensic Anthropology Center at University of Tennessee, Knoxville, to understand how nitrogen values change during decomposition after death.

While the data can assist modern forensic death investigations, in our current study we repurposed it to test a very different hypothesis. We found that stable nitrogen isotope values increase modestly as muscle tissue decomposes, ranging from -0.6 permil to 7.7 permil.

This increase is more dramatic in maggots feeding on decomposing tissue: from 5.4 permil to 43.2 permil. To put the maggot values in perspective, scientists estimate δ¹⁵N values for Pleistocene herbivores to range between 0.9 permil to 11.2 permil. Maggots are measuring up to almost four times higher.

Source: Melanie Beasley
 Created with Datawrapper

Our research suggests that the high δ¹⁵N values observed in Late Pleistocene hominins may be inflated by year-round consumption of ¹⁵N-enriched maggots found in dried, frozen or cached animal foods.

Cultural practices shape diet

In 2017, my collaborator John Speth proposed that the high δ¹⁵N values in Neanderthals were due to the consumption of putrid or rotting meat, based on historical and cultural evidence of diets in northern Arctic foragers.

Traditionally, Indigenous peoples almost universally viewed thoroughly putrefied, maggot-infested animal foods as highly desirable fare, not starvation rations. In fact, many such peoples routinely and often intentionally allowed animal foods to decompose to the point where they were crawling with maggots, in some cases even beginning to liquefy.

This rotting food would inevitably emit a stench so overpowering that early European explorers, fur trappers and missionaries were sickened by it. Yet Indigenous peoples viewed such foods as good to eat, even a delicacy. When asked how they could tolerate the nauseating stench, they simply responded, "We don't eat the smell."


Reconstruction of a Neanderthal man butchering a goat at the Neanderthal Museum in Mettman, Germany.
(Pressebilder Neanderthal Museum, Mettmann/Wikimedia Commons, CC BY-SA)



Neanderthals' cultural practices, similar to those of Indigenous peoples, might be the answer to the mystery of their high δ¹⁵N values.

Ancient hominins were butchering, storing, preserving, cooking and cultivating a variety of items. All these practices enriched their paleo menu with foods in forms that nonhominin carnivores do not consume. Research shows that δ¹⁵N values are higher for cooked foods, putrid muscle tissue from terrestrial and aquatic species, and, with our study, for fly larvae feeding on decaying tissue.

The high δ¹⁵N values of maggots associated with putrid animal foods help explain how Neanderthals could have included plenty of other nutritious foods beyond only meat while still registering δ¹⁵N values we're used to seeing in hypercarnivores.

We suspect the high δ¹⁵N values seen in Neanderthals reflect routine consumption of fatty animal tissues and fermented stomach contents, much of it in a semi-putrid or putrid state, together with the inevitable bonus of both living and dead ¹⁵N-enriched maggots.

What still isn't known

Fly larvae are a fat-rich, nutrient-dense, ubiquitous and easily procured insect resource, and both Neanderthals and early Homo sapiens, much like recent foragers, would have benefited from taking full advantage of them. But we cannot say that maggots alone explain why Neanderthals have such high δ¹⁵N values in their remains.

Several questions about this ancient diet remain unanswered. How many maggots would someone need to consume to account for an increase in δ¹⁵N values above the expected values due to meat eating alone? How do the nutritional benefits of consuming maggots change the longer a food item is stored? More experimental studies on changes in δ¹⁵N values of foods processed, stored and cooked following Indigenous traditional practices can help us better understand the dietary practices of our ancient relatives.



The birth of modern Man
https://chuckincardinal.blogspot.com/

Monday, 28 July 2025

Do Women Need More Sleep Than Men? Here's The Science.

21 July 2025. By A. SCOTT, THE CONVERSATION


(skynesher/E+/Getty Images)



If you spend any time in the wellness corners of TikTok or Instagram, you'll see claims women need one to two hours more sleep than men.

But what does the research actually say? And how does this relate to what's going on in real life?

As we'll see, who gets to sleep, and for how long, is a complex mix of biology, psychology and societal expectations. It also depends on how you measure sleep.

What does the evidence say?

Researchers usually measure sleep in two ways:by asking people how much they sleep (known as self-reporting). But people are surprisingly inaccurate at estimating how much sleep they get
using objective tools, such as research-grade, wearable sleep trackers or the gold-standard polysomnography, which records brain waves, breathing and movement while you sleep during a sleep study in a lab or clinic.

Looking at the objective data, well-conducted studies usually show women sleep about 20 minutes more than men.

One global study of nearly 70,000 people who wore wearable sleep trackers found a consistent, small difference between men and women across age groups. For example, the sleep difference between men and women aged 40–44 was about 23–29 minutes.

Another large study using polysomnography found women slept about 19 minutes longer than men. In this study, women also spent more time in deep sleep: about 23 percent of the night compared to about 14 percent for men. The study also found only men's quality of sleep declined with age.

The key caveat to these findings is that our individual sleep needs vary considerably. Women may sleep slightly more on average, just as they are slightly shorter on average. But there is no one-size-fits-all sleep duration, just as there is no universal height.

Suggesting every woman needs 20 extra minutes (let alone two hours) misses the point. It's the same as insisting all women should be shorter than all men.

Even though women tend to sleep a little longer and deeper, they consistently report poorer sleep quality. They're also about 40 percent more likely to be diagnosed with insomnia.

This mismatch between lab findings and the real world is a well-known puzzle in sleep research, and there are many reasons for it.

For instance, many research studies don't consider mental health problems, medications, alcohol use and hormonal fluctuations. This filters out the very factors that shape sleep in the real world.

This mismatch between the lab and the bedroom also reminds us sleep doesn't happen in a vacuum. Women's sleep is shaped by a complex mix of biological, psychological and social factors, and this complexity is hard to capture in individual studies.

Let's start with biology

Sleep problems begin to diverge between the sexes around puberty. They spike again during pregnancy, after birth and during perimenopause.

Fluctuating levels of ovarian hormones, particularly estrogen and progesterone, seem to explain some of these sex differences in sleep.

For example, many girls and women report poorer sleep during the premenstrual phase just before their periods, when estrogen and progesterone begin to fall.

Perhaps the most well-documented hormonal influence on our sleep is the decline in estrogen during perimenopause. This is linked to increased sleep disturbances, particularly waking at 3am and struggling to get back to sleep.

Some health conditions also play a part in women's sleep health. Thyroid disorders and iron deficiency, for instance, are more common in women and are closely linked to fatigue and disrupted sleep.

How about psychology?

Women are at much higher risk of depression, anxiety and trauma-related disorders. These very often accompany sleep problems and fatigue. Cognitive patterns, such as worry and rumination, are also more common in women and known to affect sleep.

Women are also prescribed antidepressants more often than men, and these medications tend to affect sleep.

Society also plays a role

Caregiving and emotional labour still fall disproportionately on women. Government data released this year suggests Australian women perform an average nine more hours of unpaid care and work each week than men.

While many women manage to put enough time aside for sleep, their opportunities for daytime rest are often scarce. This puts a lot of pressure on sleep to deliver all the restoration women need.

In my work with patients, we often untangle the threads woven into their experience of fatigue. While poor sleep is the obvious culprit, fatigue can also signal something deeper, such as underlying health issues, emotional strain, or too-high expectations of themselves. Sleep is certainly part of the picture, but it's rarely the whole story.

For instance, rates of iron deficiency (which we know is more common in women and linked to sleep problems) are also higher in the reproductive years. This is just as many women are raising children and grappling with the "juggle" and the "mental load".

Women in perimenopause are often navigating full-time work, teenagers, ageing parents and 3am hot flashes. These women may have adequate or even high-quality sleep (according to objective measures), but that doesn't mean they wake feeling restored.

Most existing research also ignores gender-diverse populations. This limits our understanding of how sleep is shaped not just by biology, but by things such as identity and social context.

So where does this leave us?

While women sleep longer and better in the lab, they face more barriers to feeling rested in everyday life.

So, do women need more sleep than men? On average, yes, a little. But more importantly, women need more support and opportunity to recharge and recover across the day, and at night.



The birth of modern Man
https://chuckincardinal.blogspot.com/

Human Brains Rapidly Aged in The Pandemic, And It Wasn't Just The Virus

28 July 2025, By C. CASSELLA


(baranozdemir/Getty Images)



The devastation of the COVID-19 pandemic may have left a significant mark on our brains, even if we didn't get sick.

Fatal cases of COVID-19 look scarily like old age in the brain, and now, new research suggests that the mental, social, and financial stresses of the pandemic may have aged our brains as well.

A team led by researchers at the University of Nottingham trained an AI model to recognize healthy aging in the brain, using the data of more than 15,000 adults in the UK Biobank.

The algorithm was then used to analyze the brain ages of two groups: one that had brain scans taken before the pandemic and another that had brain scans taken both before and during the pandemic.

During the pandemic, the average human brain aged five and a half months faster than it did before 2020.

"What surprised me most was that even people who hadn't had COVID showed significant increases in brain aging rates," says neurologist Ali-Reza Mohammadi-Nejad from Nottingham, who led the study.

"It really shows how much the experience of the pandemic itself, everything from isolation to uncertainty, may have affected our brain health."

The good news is that those changes may be reversible. The study only analyzed brain scans from two time points, which means that there may have been neurological recovery in the years that followed.

"We can't yet test whether the changes we saw will reverse, but it's certainly possible, and that's an encouraging thought," says neurologist Dorothee Auer from Nottingham.

What's more, just because a person's brain may have aged at a faster rate during the pandemic, doesn't mean their cognitive function was necessarily impacted. In fact, the only individuals in the study who showed decreased cognitive performance were those who were directly infected with the SARS-CoV-2 virus.

Still, the findings suggest that a major life event like a pandemic can have a significant impact on the brain, even if you don't get sick.

In the first few years of the global pandemic, millions of humans died, and billions more dealt with a tidal wave of grief, loneliness, depression, anxiety, financial stress, and sleep disturbances.

Initial research found teenagers were particularly affected by the global crisis, with the adolescent brain showing concerning signs of accelerated aging after 2020, similar to teens experiencing violence, neglect, or family dysfunction.

The Life of Earth
https://chuckincardinal.blogspot.com/

A Pill That Makes Your Blood Deadly to Mosquitoes? It’s Real – And It Works

BY BARCELONA INST. FOR GLOBAL HEALTH (ISGLOBAL), JULY 27, 2025



A common pill turns your blood into mosquito poison—and slashes malaria in the process. 
Credit: Shutterstock



A simple pill may be the latest breakthrough in the fight against malaria.

A massive study across Kenya and Mozambique found that mass administration of ivermectin—an antiparasitic drug—reduced malaria cases by 26%. The pill works in a surprising way: it makes human blood deadly to mosquitoes, killing them after they bite. This novel approach could complement traditional tools like bed nets, which have lost effectiveness due to mosquito resistance. Even better, communities reported fewer lice, scabies, and bed bugs—bonus benefits from a single monthly dose.

Ivermectin Shows Promise in Reducing Malaria Transmission

A safe and widely available drug, ivermectin, has shown promise in reducing the spread of malaria when given to entire communities. In the largest study of its kind, known as the BOHEMIA trial, researchers found a 26% drop in new malaria infections even when standard tools like bed nets were already in use. These findings highlight ivermectin’s potential to serve as an added layer of protection in malaria prevention.

The study was led by the Barcelona Institute for Global Health (ISGlobal), supported by the “la Caixa” Foundation, in collaboration with the Manhiça Health Research Centre (CISM) and the KEMRI-Wellcome Trust Research Programme. The results were published in The New England Journal of Medicine.

Malaria continues to be a major global health issue, with 263 million cases and 597,000 deaths recorded in 2023. Existing prevention tools such as long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are becoming less effective. This is largely due to mosquitoes developing resistance to insecticides and changing their behavior to bite outdoors or during times when people are not shielded by these methods. These challenges have created an urgent demand for new approaches to stop the disease.


Ivermectin tablets used for the BOHEMIA trial in Kenya. 
Credit: Life Spark Studios/BOHEMIA project



Ivermectin’s Unexpected Role in Fighting Malaria

Ivermectin is typically used to treat neglected tropical diseases such as onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis). However, studies have shown that it can also reduce malaria by killing mosquitoes that bite people who have taken the drug. As resistance to insecticides increases, ivermectin may offer a new and effective way to reduce transmission, especially in areas where standard methods are no longer reliable.

The BOHEMIA project (Broad One Health Endectocide-based Malaria Intervention in Africa), funded by Unitaid, tested this idea through two large-scale Mass Drug Administration (MDA) trials in regions with high malaria burden: Kwale County in Kenya and Mopeia district in Mozambique. Researchers evaluated whether giving a single monthly dose of ivermectin (400 mcg/kg) over three months at the start of the rainy season could lower malaria transmission. In Kenya, the program focused on children aged 5 to 15, while in Mozambique it targeted children under the age of five.

Kenya Sees Clear Impact from Ivermectin

In Kwale County, Kenya, children who received ivermectin experienced a 26% reduction in malaria infection incidence compared to those who received albendazole, the control drug used in the study. The trial involved over 20,000 participants and more than 56,000 treatments, demonstrating that ivermectin significantly reduced malaria infection rates—particularly among children living further from cluster borders or in areas where drug distribution was more efficient. Moreover, the safety profile of ivermectin was favourable, with no severe drug-related adverse events and only mild, transient side effects already seen with ivermectin in campaigns against neglected tropical diseases.

“We are thrilled with these results,” says Carlos Chaccour, co-principal investigator of the BOHEMIA project and ISGlobal researcher at the time of the study. “Ivermectin has shown great promise in reducing malaria transmission and could complement existing control measures. With continued research, ivermectin MDA could become an effective tool for malaria control and even contribute to elimination efforts,” Chaccour, who is now a researcher at the Navarra Centre for International Development at the University of Navarra, adds.

“These results align with the World Health Organization’s (WHO) criteria for new vector control tools,” states Joseph Mwangangi, from the KEMRI-Wellcome Trust Research Programme. “The findings suggest that ivermectin MDA could be a valuable complementary strategy for malaria control, particularly in areas where mosquito resistance to insecticides is a growing concern,” adds Marta Maia, BOHEMIA’s lead entomologist from the University of Oxford.

Lessons and Setbacks in Mozambique Deployment

In contrast, the implementation of the Mozambique trial in the rural district of Mopeia faced severe disruptions due to Cyclone Gombe (2022) and a subsequent cholera outbreak, which significantly disrupted operations. “One of the most important lessons we learned from the trial in Mopeia is that strong community engagement is essential,” states Francisco Saúte, director of the Manhiça Health Research Centre (CISM). “Building trust with local communities and fostering close collaboration with the Health Ministry, National Malaria Control Program, and local authorities was key to ensuring acceptance of the ivermectin MDA.”

Collateral Public Health Benefits Beyond Malaria

In addition to reducing malaria transmission, ivermectin MDA offers significant collateral benefits. The BOHEMIA team found an important reduction in the prevalence of skin infestations such as scabies and head lice in the ivermectin group in Mozambique, and the community reported a major reduction in bed bugs in Kenya. These effects are particularly valuable when ivermectin is integrated into existing delivery systems, maximising its impact on public health.

Toward a New Era of Malaria Control Strategy

The study is part of a larger global effort to assess ivermectin’s potential in malaria control. The findings have been reviewed by the WHO vector control advisory group, which concluded that the study had demonstrated impact and recommended further studies. Findings were also shared with national health authorities as they evaluate the potential inclusion of ivermectin in malaria control programmes.

“This research has the potential to shape the future of malaria prevention, particularly in endemic areas where existing tools are failing,” concludes Regina Rabinovich, BOHEMIA PI and Director of ISGlobal’s Malaria Elimination Initiative. “With its novel mechanism of action and proven safety profile, ivermectin could offer a new approach using a well-known, safe drug that can add to the effect of other mosquito control tools available today.”



The Life of Earth
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